Biotechnological production of prostaglandins

Lamacka M; Sajbidor J

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Biotechnological production of prostaglandins

机译：前列腺素的生物技术生产

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摘要

The metabolism of 20-carbon polyunsaturated fatty acids, particularly arachidonic acid, by prostaglandin H synthase results in a wide range of oxidized products with potent biological activities. Among these metabolites, a group of compounds called prostaglandins has drawn the attention of both scientists and medical practitioners. Prostaglandins can be manufactured from polyunsaturated fatty acids with the help of enzymes from mammals. The yield of the desired prostaglandin can be increased by means of various activators, enzyme recycling, immobilised enzymes or semibatch processes with either continuous or stepwise addition of the substrate.

机译：前列腺素H合酶代谢20-碳的多不饱和脂肪酸，特别是花生四烯酸，产生具有有效生物活性的多种氧化产物。在这些代谢产物中，一组称为前列腺素的化合物引起了科学家和医学从业者的注意。前列腺素可以在哺乳动物的酶的帮助下由多不饱和脂肪酸制成。可以通过各种活化剂，酶循环，固定化酶或通过连续或逐步加入底物的半间歇方法来提高所需前列腺素的产率。

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来源
《Applied Microbiology and Biotechnology》 |1997年第3期|共8页
作者
Lamacka M; Sajbidor J;
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原文格式 PDF
正文语种 eng
中图分类微生物学;
关键词
PGH-PGD ISOMERASE; ARACHIDONIC-ACID; H SYNTHASE; BIOSYNTHESIS; PURIFICATION; EICOSANOIDS; SYNTHETASE;

机译：PGH-PGD异构酶;花生四烯酸;H合酶;生物合成;纯化;二十碳五烯酸;合成酶;

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1. Biotechnological approach towards a highly efficient production of natural prostaglandins [J] . Guder J. C., Buchhaupt M., Huth I., Biotechnology Letters . 2014,第11期

机译：高效生产天然前列腺素的生物技术方法
2. Biotechnological production of prostaglandin [Review] [J] . Yilmaz E. Biotechnology Advances: An International Review Journal . 2001,第5期

机译：前列腺素的生物技术生产[综述]
3. Biotechnological production of prostaglandin. [J] . Yilmaz E Biotechnology Advances: An International Review Journal . 2001,第5期

机译：前列腺素的生物技术生产。
4. Effect of ovarian steroids and oxytocin on local production of prostaglandin E_2, prostaglandin F_2#alpha# and endothelin-1 in cow oviductal epithelia cell monolayers. [C] . M.P.B. WIJAYAGUNAWARDANE, Y.H. CHOI, A.MIYAMOTO, Joint International Meeting of the Japanese Association for Animal Cell Technolog and and European Society for Animal Cell Technology . 1999

机译：卵巢类固醇和催产素对牛卵籽上皮细胞单层中前列腺素E_2，前列腺素F_2＃α＃和内皮素-1的影响。
5. Prostaglandin H synthase catalyzes the oxidation of 4-chlorobiphenyl metabolites, and the in vivo effects on prostaglandin production [D] . Wangpradit, Orarat 2011

机译：前列腺素H合酶催化4-氯联苯代谢物的氧化，以及体内对前列腺素生产的影响
6. The rise of health biotechnology research in Latin America: A scientometric analysis of health biotechnology production and impact in Argentina, Brazil, Chile, Colombia, Cuba and Mexico [O] . Dante Israel León-de la O, Halla Thorsteinsdóttir, José Víctor Calderón-Salinas 2012

机译：拉丁美洲健康生物技术研究的兴起：对阿根廷，巴西，智利，哥伦比亚，古巴和墨西哥的健康生物技术生产及其影响的科学计量分析
7. Enzymatic biofuel cells : biotechnology for energy production with biomedical and biotechnological applications [O] . Valle Julieta del 2015

机译：酶促生物燃料电池：利用生物医学和生物技术应用生产能量的生物技术
8. Problems Connected with the Production of Highly Specific Antisera Against Prostaglandin E sub 2 (PGE Sub 2 ) and Prostaglandin A sub 2 (PGA Sub 2 ) for Radioimmunoassay [R] . Kopp, H. G., Vetter, W., Siegenthaler, W. 1977

机译：与针对前列腺素E sub 2（pGE sub 2）和prostaglandin a sub 2（pGa sub 2）的放射免疫测定产生高度特异性抗血清相关的问题

Biotechnological production of prostaglandins

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