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首页> 外文期刊>Anticancer Research: International Journal of Cancer Research and Treatment >Clinical significance of cell-free and concentrated ascites re-infusion therapy for advanced and recurrent gynecological cancer.
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Clinical significance of cell-free and concentrated ascites re-infusion therapy for advanced and recurrent gynecological cancer.

机译：无细胞浓缩腹水再输注治疗晚期和复发性妇科癌症的临床意义。

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摘要

The management of malignant ascites is critical for the treatment of patients with advanced gynecological cancer. The purpose of this study was to assess the clinical significance of cell-free and concentrated ascites re-infusion therapy (CART).Adverse events, alterations in Eastern Cooperative Oncology Group performance status, serum albumin, body weight and abdominal circumference, and overall survival were examined in 22 patients with advanced gynecological cancer which were treated with CART.Most of the adverse events were grade 1 or 2 fever. CART treatment had little effect on ECOG performance status and on levels of serum albumin. There was a significant decrease in body weight and in abdominal circumference post-treatment with CART, relative to pre-treatment (p<0.01). The overall survival rate was significantly prolonged in 14 patients after CART plus chemotherapy, as compared with eight patients after CART alone (p<0.01).CART may contribute to the improvement of quality of life and of survival in patients with advanced gynecological cancer.
机译：恶性腹水的管理对于晚期妇科癌症患者的治疗至关重要。这项研究的目的是评估无细胞浓缩腹水再输注治疗（CART）的临床意义。不良事件，东部合作肿瘤小组工作状态的改变，血清白蛋白，体重和腹围以及总体生存在接受CART治疗的22例晚期妇科癌症患者中进行了检查。大多数不良事件为1级或2级发烧。 CART治疗对ECOG表现状态和血清白蛋白水平影响很小。与治疗前相比，CART治疗后的体重和腹围明显减少（p <0.01）。与单纯接受CART治疗后的8例患者相比，接受CART +化疗后的14例患者的总生存率显着延长（p <0.01）.CART可能有助于改善晚期妇科癌症患者的生活质量和生存率。

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