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首页> 外文期刊>Anticancer Research: International Journal of Cancer Research and Treatment >Disease-free interval after primary treatment predicts prognosis of recurrent endometrial carcinoma.
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Disease-free interval after primary treatment predicts prognosis of recurrent endometrial carcinoma.

机译：初次治疗后无病间隔可预测复发性子宫内膜癌的预后。

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AIM: The aim of this study was to determine if the disease-free interval after initial surgical resection has any useful prognostic value for recurrent endometrial carcinoma patients. PATIENTS AND METHODS: Between 1998 and 2007, complete resection of endometrial carcinoma was achieved in 536 cases at the Departments of Obstetrics and Gynecology of the Osaka University and Osaka Rosai Hospitals of Osaka, Japan. Clinical characteristics of these cases were retrospectively reviewed. RESULTS: Recurrence was subsequently detected in 54 cases. Overall survival after recurrence in 27 patients with recurrences earlier than 12 months who received no postoperative therapy, radiation, and chemotherapy as an adjuvant therapy were significantly shorter than that of those with recurrences later than 12 months with similar treatments. Multivariate analysis demonstrated that the disease-free interval was an independent factor for prognosis. CONCLUSION: We demonstrate a significantly worse prognosis in cases with early versus late recurrence of resected endometrial carcinomas, irrespective of the type of adjuvant therapy.
机译：目的：本研究的目的是确定初次手术切除后无病间隔对复发性子宫内膜癌患者是否有任何有用的预后价值。患者与方法：1998年至2007年，在大阪大学的妇产科和日本大阪的大阪Rosai医院完成了536例子宫内膜癌的完全切除。回顾性分析这些病例的临床特征。结果：54例患者随后被发现复发。在没有接受术后治疗，放疗和化疗作为辅助治疗的27例复发时间早于12个月的复发患者中，复发后的总生存期明显短于在类似治疗之后的12个月后复发的患者。多变量分析表明，无病间隔是预后的独立因素。结论：无论辅助治疗的类型如何，我们均显示子宫内膜癌切除术后早期和晚期复发的预后明显较差。

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