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首页> 外文期刊>Archives of disease in childhood >Are annual blood tests in preschool cystic fibrosis patients worthwhile?
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Are annual blood tests in preschool cystic fibrosis patients worthwhile?

机译：学龄前囊性纤维化患者的年度血液检查值得吗？

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Aim: To investigate whether routine annual assessment blood tests in cystic fibrosis (CF) patients under 5 years influence management. METHODS: Retrospective review of the results of the first annual assessment blood tests of patients with CF less than 5 years of age during a four year period (1995-99). Management changes were identified from a follow up letter to the general practitioner or local paediatrician. RESULTS: A total of 169 patients (100 female), median age 2.2 years (range 0.3-4.9) were identified. Venepuncture was successful in 93% of patients. Of the 32 individual blood parameters measured, the overall success rate in obtaining a result was 81%. Eleven per cent of patients underwent subsequent management changes, including liver ultrasound, fasting glucose, and a short course of iron. Of particular importance, vitamin A and E concentrations were low in 9% of patients, which prompted an increase in prescribed dose. CONCLUSIONS: These results support the recommendations for routine blood tests at annual review in preschool CF children. The results may help to rationalise which tests are performed and thus reduce laboratory costs.
机译：目的：调查5岁以下的囊性纤维化（CF）患者的年度例行血液检查是否对治疗产生影响。方法：回顾性回顾四年（1995-99年）内年龄小于5岁的CF患者的首次年度评估血液测试结果。在写给全科医生或当地儿科医生的跟进信中确定了管理变更。结果：总共鉴定出169名患者（100名女性），中位年龄2.2岁（范围0.3-4.9）。静脉穿刺术在93％的患者中成功。在所测量的32个个体血液参数中，获得结果的总体成功率为81％。 11％的患者随后进行了管理变更，包括肝脏超声检查，空腹血糖和短期铁疗。特别重要的是，9％的患者维生素A和E浓度较低，这促使处方剂量增加。结论：这些结果支持对学龄前CF儿童进行年度检查时常规血液检查的建议。结果可能有助于合理化执行哪些测试，从而降低实验室成本。

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