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首页> 外文期刊>Arthritis and Rheumatism >Prevalence and sex difference of lumbar disc space narrowing in elderly chinese men and women: Osteoporotic fractures in men (Hong Kong) and osteoporotic fractures in women (Hong Kong) studies
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Prevalence and sex difference of lumbar disc space narrowing in elderly chinese men and women: Osteoporotic fractures in men (Hong Kong) and osteoporotic fractures in women (Hong Kong) studies

机译：中国老年男女腰椎间盘狭窄的患病率和性别差异：男性骨质疏松性骨折（香港）和女性骨质疏松性骨折（香港）研究

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Objective Osteoporotic Fractures in Men (Hong Kong) and Osteoporotic Fractures in Women (Hong Kong) represent the first large-scale prospective population-based studies on bone health in elderly (age ≥65 years) Chinese men (n = 2,000) and women (n = 2,000). We undertook the current study to investigate the prevalence of lumbar disc space narrowing in these subjects, and to identify the potential relationship between disc space narrowing and sex, bone mineral density (BMD), and other demographic and clinical data. Methods On lumbar lateral radiographs, L1/L2-L4/L5 disc space was classified into 4 categories: 0 = normal; 1 = mild narrowing; 2 = moderate narrowing; 3 = severe narrowing. We compared demographic and clinical data between subjects with and those without total disc space narrowing scores ≥3. Results Disc space narrowing was more common in elderly women than in elderly men. The mean ± SD disc space narrowing score for the 4 discs was 2.71 ± 2.21 for men and 3.08 ± 2.50 for women (P < 0.0001). For the 3 age groups of 65-69 years, 70-79 years, and ≥80 years, the average disc space narrowing score increased with increasing age in both men and women, and to a greater degree in women than in men. The average disc space narrowing score differences between women and men were 0.12, 0.40, and 0.90, respectively, in the 3 age groups. For both men and women, a disc space narrowing score ≥3 was associated with older age, higher spine and hip BMD, low back pain, and restricted leg mobility. Conclusion The prevalence and severity of disc space narrowing are higher in elderly women than in elderly men. With increasing age, disc space narrowing progresses at a greater rate in women than in men. A disc space narrowing score ≥3 is associated with higher spine and hip BMD.
机译：客观的男性骨质疏松性骨折（香港）和女性骨质疏松性骨折（香港）代表了针对老年人（≥65岁）的中国男性（n = 2,000）和女性（ n = 2,000）。我们进行了当前的研究，以调查这些受试者中腰椎间盘间隙狭窄的患病率，并确定椎间盘间隙狭窄与性别，骨矿物质密度（BMD）以及其他人口统计学和临床​​数据之间的潜在关系。方法在腰椎侧位片上，将L1 / L2-L4 / L5椎间盘间隙分为4类：0 =正常; 0 =正常; 0 =正常。 1 =轻微收窄; 2 =适度收窄; 3 =严重缩小。我们比较了总椎间盘空间狭窄评分≥3的受试者和没有椎间盘狭窄的受试者的人口统计学和临床​​数据。结果老年妇女的椎间盘间隙变窄比老年男性更普遍。 4片椎间盘的平均±SD椎间盘狭窄评分为男性为2.71±2.21，女性为3.08±2.50（P <0.0001）。在65-69岁，70-79岁和≥80岁这3个年龄组中，男性和女性的平均椎间盘间隙缩小分数均随年龄的增加而增加，而女性的比例要高于男性。在3个年龄组中，男女之间的平均椎间盘间隙变窄得分分别为0.12、0.40和0.90。对于男性和女性，椎间盘间隙缩小分数≥3与年龄较大，脊柱和髋部BMD升高，腰痛和下肢活动受限有关。结论老年妇女的椎间盘间隙狭窄的患病率和严重程度高于老年男性。随着年龄的增长，女性的椎间盘间隙缩小速度要比男性快。椎间盘狭窄分数≥3与较高的脊柱和髋部BMD有关。

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