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Changes in vein dynamics ranging from low to high pressure levels as a determinant of the differences in vein adaptation to arterial hemodynamic conditions.

机译:静脉动力学的变化范围从低到高,这决定了静脉对动脉血液动力学状况的适应性差异。

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摘要

The causes of the regional differences in venous grafts patency rates are partially understood. Differences in vein dynamics during physiological situations could determine differences in veins' capability to face arterial conditions and could contribute to the dissimilar performance of veins as arterial grafts. In vitro pressure and diameter were measured in four different veins during physiological and arterial (graft) pressure conditions. A diameter-pressure transfer function was designed. Compliance, viscous and inertial properties; circumferential stresses and deformation; and buffering function were calculated. Regional differences in veins' dynamics, but not in buffering function were found during physiological and arterial conditions. The back vein (femoral) showed the least changes when submitted to arterial conditions. Arterial conditions represent different changes in vein dynamics depending on the segment considered. The regional differences in vein dynamics, both at physiological and graftconditions, could contribute to explain the dissimilar results of venous grafts.
机译:部分了解静脉移植物通畅率区域差异的原因。生理情况下静脉动力的差异可能决定静脉面对动脉状况的能力差异,并可能导致静脉作为动脉移植物的性能有所不同。在生理和动脉(移植)压力条件下,在四个不同的静脉中测量了体外压力和直径。设计了直径-压力传递函数。柔度,粘性和惯性;圆周应力和变形;计算缓冲功能。在生理和动脉疾病期间,发现了静脉动力学的区域差异,但没有发现缓冲功能。当经受动脉疾病时,后静脉(股骨)的变化最小。动脉状况取决于所考虑的部位,代表了静脉动力学的不同变化。在生理和移植条件下,静脉动力学的区域差异可能有助于解释静脉移植物的不同结果。

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