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首页> 外文期刊>Annals of Human Biology: Journal of the Society for the Study of Human Biology >Ecological and sociodemographic effects on urinary catecholamine excretion in adult Samoans
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Ecological and sociodemographic effects on urinary catecholamine excretion in adult Samoans

机译：生态和社会人口学特征对成年萨摩亚人尿儿茶酚胺排泄的影响

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Background: Ecological and sociodemographic correlates of stress may contribute to cardiovascular disease risk in modernizing Samoans. Aim: The effects of peri-urban vs rural residence, education, occupation, caffeine intake and cigarette consumption on urinary catecholamine excretion were studied in Samoan adults. Subjects and methods: Five hundred and seven participants, aged 29-69 years, were randomly selected from nine villages throughout Samoa. Sociodemographic and lifestyle factors were assessed by questionnaire. Epinephrine and norepinephrine excretion rates were measured by high performance liquid chromatography with electrochemical detection in overnight urine samples. Age (≤40 vs >40 years) and gender-specific regression models were estimated to detect associations with BMI-adjusted catecholamine excretion. Results: Norepinephrine was significantly higher in peri-urban young men and older women. Epinephrine was significantly higher in peri-urban older men. Adjustment for caffeine attenuated the relationship between residence and norepinephrine in young women. Conclusion: General residential exposure to modernization in urban villages is a significant correlate of increased overnight catecholamine excretion rates and is consistent with past studies. Caffeine consumption in younger women plays a complex role in stress-related catecholamine excretion. Further studies of individual level attitudinal and behavioural factors in Samoans are needed to understand psychosocial stress, physiologic arousal and health.
机译：背景：压力的生态和社会人口统计学相关性可能导致萨摩亚人现代化的心血管疾病风险。目的：在萨摩亚成年人中研究了城郊与农村居民，教育程度，职业，咖啡因摄入量和香烟消费对儿茶酚胺排泄的影响。受试者和方法：随机从萨摩亚的9个村庄中选出了29位至69岁的507位参与者。通过问卷调查评估了社会人口统计学和生活方式因素。尿液中肾上腺素和去甲肾上腺素的排泄率是通过高效液相色谱法和电化学检测法测定的。估计年龄（≤40 vs> 40岁）和特定性别的回归模型以检测与BMI调整的儿茶酚胺排泄的相关性。结果：去甲肾上腺素在城郊青年和老年妇女中明显更高。肾上腺素在城郊老年男性中明显更高。对咖啡因的调节减弱了年轻女性中居住和去甲肾上腺素之间的关系。结论：城市村庄中一般居民对现代化的接触与过夜儿茶酚胺排泄率增加有显着相关性，并且与过去的研究一致。年轻妇女摄入咖啡因在与压力有关的儿茶酚胺排泄中起着复杂的作用。需要进一步研究萨摩亚人的个人态度和行为因素，以了解社会心理压力，生理唤醒和健康状况。

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