Genomics and milk.

German J. B.

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Genomics and milk.

机译：基因组学和牛奶。

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Genomics, proteomics and metabolomics are providing the tools to assess human health, but what knowledge resource can guide scientific research to improve it? The Darwinian selective pressure on lactation to promote the competitive success of offspring drove the emergence of nutritional strategies that go beyond the simple provision of essential nutrients. Identifying the molecules, mechanisms and health benefits encrypted in milk is the goal of milk genomics. Variations in gene expression during lactation reveal principles of lactation and some surprises. There is apparently no lactation switch, most milk-specific genes are induced gradually during pregnancy. The genes down regulated during lactation are also intriguing, ubiquitination is turned off. Milk provides remarkable insights into health promotion. Oligosaccharides in human milk selectively support the growth of Bifidobacteria longum subspecies infantis. Its genome is revealing evidence of the co-evolution of milk and commensal bacteria and new genes with potential benefits to human health.

机译：基因组学，蛋白质组学和代谢组学为评估人类健康提供了工具，但是哪些知识资源可以指导科学研究以改善人类健康？达尔文关于泌乳的选择性压力，以促进后代的竞争成功，推动了营养策略的出现，这些营养策略超出了简单提供必需营养素的范围。鉴定牛奶中加密的分子，机制和健康益处是牛奶基因组学的目标。哺乳期间基因表达的变化揭示了哺乳的原理和一些惊喜。显然没有泌乳开关，大多数牛奶特异性基因是在怀孕期间逐渐诱导的。哺乳期间下调的基因也很有趣，泛素化被关闭了。牛奶为促进健康提供了非凡的见解。人乳中的低聚糖选择性地支持长双歧杆菌亚种ini fantis的生长。它的基因组揭示了牛奶和共生细菌以及对人类健康有潜在益处的新基因共同进化的证据。

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《Australian Journal of Dairy Technology》 |2009年第1期|共8页
作者
German J. B.;
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正文语种 eng
中图分类畜牧、动物医学、狩猎、蚕、蜂;
关键词
dairy technology; gene expression; genes; health; health promotion; human milk; lactation; milk; milk processing; nutrients; oligosaccharides; pregnancy; Bacteria; Bifidobacterium; man;

机译：乳制品技术;基因表达;基因;健康;促进健康;人乳;哺乳期;牛奶;牛奶加工;营养素;低聚糖;怀孕;细菌;双歧杆菌;人;

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1. Development of a random genomic DNA microarray for the detection and identification of Listeria monocytogenes in milk. [J] . Bang JiHyun, Beuchat L. R., Song Han, International Journal of Food Microbiology . 2013,第2期

机译：用于检测和鉴定牛奶中李斯特菌的随机基因组DNA微阵列的开发。
2. The genomic data deficit: On the need to inform research subjects of the informational content of their genomic sequence data in consent for genomic research [J] . Hallinan Dara Computer law & security report . 2020,第Jula期

机译：基因组数据赤字：关于在基因组研究的同意中通知其基因组序列数据的信息内容的研究主题
3. RICHARD M. SIMON . Genomic Clinical Trials and Predictive Medicine . Cambridge : Cambridge University Press . RICHARD M. SIMON RICHARD M. SIMON . Genomic Clinical Trials and Predictive Medicine Genomic Clinical Trials and Predictive Medicine . Cambridge Cambridge : Cambridge University Press Cambridge University Press . [J] . Matsui Shigeyuki Biometrics: Journal of the Biometric Society : An International Society Devoted to the Mathematical and Statistical Aspects of Biology . 2018,第2期

机译：Richard M. Simon。基因组临床试验和预测医学。剑桥：剑桥大学出版社。 Richard M. Simon Richard M. Simon。基因组临床试验及预测医学基因组临床试验及预测医学。剑桥剑桥：剑桥大学新闻出版社剑桥大学出版社。
4. Highly sensitive surface-enhanced Raman scattering detection of brodifacoum and 1080 rodenticide in milk. [C] . Megha Mehta, Mark R. Waterland SPIE Conference on Nanoimaging and Nanospectroscopy . 2018

机译：高敏感的表面增强拉曼散射检测Brodifacoum和1080个臭肽在牛奶中。
5. Communicating Legacy: Media, Memory and Harvey Milk. [D] . Mau, Heidi A. 2017

机译：传承传统：媒体，记忆和哈维·米尔克。
6. Bacteriostasis of Escherichia coli by milk. IV. The bacteriostatic antibody of human milk. [O] . J. M. Dolby, P. Honour 1979

机译：牛奶对大肠杆菌的抑菌作用。 IV。人乳的抑菌抗体。
7. Bacteriostasis of Escherichia coli by milk. IV. The bacteriostatic antibody of human milk. [O] . Dolby, J. M., Honour, P. 1979

机译：牛奶对大肠杆菌的抑菌作用。 IV。人乳的抑菌抗体。
8. Why are Americans Consuming Less Fluid Milk. A Look at Generational Differences in Intake Frequency. [R] . Stewart, H., Dong, D., Carlson, A. 2013

机译：为什么美国人消耗更少的乳液。关于摄入频率的代际差异。

Genomics and milk.

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