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首页> 外文期刊>Brain: A journal of neurology >Semicircular canal plane head impulses detect absent function of individual semicircular canals.
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Semicircular canal plane head impulses detect absent function of individual semicircular canals.

机译:半圆管平面头脉冲检测单个半圆管的功能缺失。

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摘要

We studied the human vestibulo-ocular reflex (VOR) in response to head 'impulses': brief, unpredictable, passive, high-acceleration (up to 4000 degrees/s2), low-amplitude (20-30 degrees) head rotations. We delivered the head impulses approximately in the plane of the semicircular canal (SCC) being tested. To test the anterior and posterior SCCs, the head impulses were delivered in a diagonal plane, midway between the frontal (roll) and sagittal (pitch) planes. We recorded head and eye position in three dimensions with scleral search coils in nine normal subjects, seven patients following unilateral surgical vestibular neurectomy and three patients following unilateral posterior SCC occlusion. In the post-surgical patients we demonstrated a severe, permanent VOR gain deficit (0.2-0.3) for head impulses directed toward any single non-functioning SCC. The sensitivity of the test depends on the physiological properties of primary vestibular afferents, and its specificity depends on the anatomical orientation of the SCCs. The diagonal head impulse is the first test of individual vertical SCC function in humans, and together with the horizontal head impulse, forms a comprehensive battery of SCC-plane tests. These canal-plane impulses could be useful in evaluating patients with vertigo or other vestibular disorders.
机译:我们研究了响应头部“冲动”的人类前庭眼反射(VOR):短暂,不可预测,被动,高加速度(最高4000度/ s2),低振幅(20-30度)头部旋转。我们大约在被测试的半规管(SCC)平面中传递头部脉冲。为了测试前部和后部SCC,将头部脉冲传递到对角线平面中,该对角线平面位于额部(横滚)和矢状(俯仰)平面之间。我们在9个正常受试者,7例单侧外科前庭神经切除术后的患者和3例单侧后SCC闭塞患者的巩膜搜索线圈中记录了头和眼的三维位置。在外科手术后的患者中,我们发现针对任何单个无功能SCC的头部冲动都存在严重的永久性VOR增益不足(0.2-0.3)。测试的敏感性取决于原发前庭传入的生理特性,其特异性取决于SCC的解剖学方向。斜头冲动是人类对单个垂直SCC功能的首次测试,并且与水平头冲动一起构成了SCC平面测试的综合电池。这些运河平面的冲动可用于评估患有眩晕或其他前庭疾病的患者。

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