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Clear cell carcinoma of the nasal cavity: A case report from histopathological viewpoint

机译:鼻腔透明细胞癌的组织病理学报道

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摘要

We report an extremely rare case of primary clear cell carcinoma (CCC), not otherwise specified (NOS) of the nasal cavity. An 80-year-old woman was referred to our hospital with left nasal obstruction caused by a nasal cavity tumor. The tumor was resected completely with lateral rhinotomy approach. Histopathological examination revealed CCC. CCC metastasis from renal cell carcinoma (RCC), which is at the top of differential diagnosis, was ruled out by the absence of renal tumor at computed tomography (CT). Also, immunohistochemical results of the specimen with vimentin negative and CK7 focally positive excluded the possibility of RCC metastasis. The patient is free from recurrence 1 year after the surgery, and there is no evidence of RCC. In this report histopathological characteristics, especially immunohistochemical properties of primary CCC, NOS of the nasal cavity are presented together with some clinical features of this rare tumor. Also, we refer to histopathogenesis of primary CCC of nasal cavity in relation to myoepithelial carcinoma. Histopathological discussion is further extended to include other CCC and CCC-resembling histologies to confirm the uniqueness of the present case. (C) 2015 Published by Elsevier Ireland Ltd.
机译:我们报告的鼻腔原发性透明细胞癌(CCC),未另作规定(NOS)的极少数情况。一名80岁妇女因鼻腔肿瘤引起的左鼻阻塞被转诊到我们医院。鼻侧切开术将肿瘤完全切除。组织病理学检查显示CCC。肾细胞癌(RCC)的CCC转移是鉴别诊断的重中之重,这是因为计算机断层扫描(CT)中没有肾肿瘤而被排除。此外,波形蛋白阴性和CK7局灶性阳性的标本的免疫组织化学结果排除了RCC转移的可能性。手术后1年,患者无复发,也没有RCC的证据。在本报告中,介绍了这种罕见肿瘤的组织病理学特征,尤其是原发性CCC,鼻腔NOS的免疫组织化学性质以及一些临床特征。另外,我们指的是与肌上皮癌有关的鼻腔原发性CCC的组织病理学。组织病理学讨论进一步扩展到包括其他CCC和类似CCC的组织学,以确认本案的独特性。 (C)2015由Elsevier Ireland Ltd.发布

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