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首页> 外文期刊>Innovations: technology and techniques in cardiothoracic and vascular surgery >VATS Thymectomy for Nonthymomatous Myasthenia Gravis Standardized Outcome Assessment Using the Myasthenia Gravis Foundation of America Clinical Classification
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VATS Thymectomy for Nonthymomatous Myasthenia Gravis Standardized Outcome Assessment Using the Myasthenia Gravis Foundation of America Clinical Classification

机译：使用美国重症肌无力基金会临床分类的非胸腺性重症肌无力重症患者的VATS胸腺切除术

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Objective: Video-assisted thoracoscopic (VATS) thymectomy has been practiced in Australia for nearly two decades. Our aim was to assess the complete stable remission and asymptomatic disease rates after VATS thymectomy in nonthymomatous myasthenia gravis. There remains doubt that minimally invasive techniques achieve equal remission rates to open maximal operations. Therefore, we report our outcomes using the Myasthenia Gravis Foundation of America (MGFA) Clinical Classification and Kaplan-Meier analysis and compare the results to the literature.Methods: A retrospective analysis of 78 consecutive patients undergoing right VATS Ihymectomy between April 1994 and March 2007 at two Thoracic Surgery Units in Melbourne, Australia, was undertaken. Patients with thymoma were excluded. Therefore, 57 patients were followed-up for a minimum of 12 months to apply the MGFA Clinical Classification. VATS thymectomy was performed by a three-port right side technique. Results: The complete stable remission rate was 15% at 3 years and 28% at 5 years. The asymptomatic disease rate was 59% at 5 years. Median follow-up was 32 months. No prognostic factors for remission were identified. The overall morbidity rate was 14% (8/57). Conclusions: Right VATS thymectomy achieves comparable remission and asymptomatic disease rates to other minimally invasive and open techniques when compared with studies using either MGFA or older criteria.
机译：目的：电视辅助胸腔镜（VATS）胸腺切除术在澳大利亚已经实施了近二十年。我们的目标是评估非胸腺性重症肌无力的VATS胸腺切除术后完全稳定的缓解和无症状疾病发生率。仍然有疑问，微创技术能否达到相等的缓解率，以实现最大的手术效果。因此，我们使用美国重症肌无力基金会（MGFA）临床分类和Kaplan-Meier分析报告了我们的结果，并将结果与​​文献进行了比较。方法：回顾性分析1994年4月至2007年3月间78例接受右VATS瓣膜切除术的患者在澳大利亚墨尔本的两个胸外科室进行了手术。胸腺瘤患者被排除在外。因此，对57位患者进行了至少12个月的随访，以应用MGFA临床分类。 VATS胸腺切除术通过三端口右侧技术进行。结果：3年的完全稳定缓解率分别为15％和5年的28％。 5年时无症状疾病率为59％。中位随访时间为32个月。未发现缓解的预后因素。总体发病率为14％（8/57）。结论：与使用MGFA或更旧标准的研究相比，右VATS胸腺切除术可达到与其他微创和开放技术相当的缓解率和无症状疾病率。

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