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Traumatic brain injury: neuroprotective anaesthetic techniques, an update

机译：颅脑外伤：神经保护麻醉技术，更新

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摘要

Traumatic brain injuries remain an area of great challenge to both neurosurgeons and neuroanaesthesiologists. The management of these injuries starts at the scene of the accident. However, strategies for preventing secondary brain injury and its sequelae are continuing to evolve. These strategies include the use of pharmacological and nonpharmacological techniques. Preventing hypoxia and the use of hypertonic saline have been shown to have favourable results on the outcome of these injuries. The use of isoflurane has been shown to have a neuronprotective effect. Propofol is thought to be the future drug of choice because of its neuroprotective properties, although these still need to be further proven through research. In this review an understanding of the pathophysiology of traumatic brain injury will be outlined in order to understand the effects of pharmacological and nonpharmacological agents on secondary brain injury.
机译：颅脑外伤仍然是神经外科医师和神经麻醉医师面临的巨大挑战。这些伤害的管理始于事故现场。但是，预防继发性脑损伤及其后遗症的策略正在不断发展。这些策略包括使用药理学和非药理学技术。事实证明，预防缺氧和高渗盐水的使用对这些伤害的结果具有良好的效果。已经显示异氟烷的使用具有神经保护作用。丙泊酚由于其神经保护特性而被认为是未来的首选药物，尽管这些仍需要通过研究进一步证明。在这篇综述中，将概述对创伤性脑损伤的病理生理学的理解，以了解药理和非药理学试剂对继发性脑损伤的影响。

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