NADH dehydrogenase subunit 4 variant sequences in childhood acute myeloid leukaemia

MorganM.A.; MarkusB.; HermkensM.; DammF.; ReinhardtD.; ZimmermannM.; TholF.; BunkeT.; BogoevaD.; ReuterC.W.M.; deHaasV.; vandenHeuvel-EibrinkM.M.; ZwaanC.M.; ReinhardtK.

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NADH dehydrogenase subunit 4 variant sequences in childhood acute myeloid leukaemia

机译：儿童急性髓性白血病中NADH脱氢酶亚基4变异序列

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Somatic mutations affecting genes implicated in metabolic regulation, such as isocitrate dehydrogenases (IDH1/IDH2) and mitochondrially encoded NADH dehydrogenase 4 (MT-ND4), were recently discovered by sequencing an adult, acute myeloid leukaemia (AML) genome (Mardis et al, 2009). MT-ND4 is an integral component of Complex I, a core enzymatic complex critical for mitochondrial oxidative phosphorylation and regulation of NADH/NAD+ levels.

机译：最近通过对成人急性髓细胞白血病（AML）基因组进行测序，发现了影响代谢调控基因的体细胞突变，例如异柠檬酸脱氢酶（IDH1 / IDH2）和线粒体编码的NADH脱氢酶4（MT-ND4）。 2009）。 MT-ND4是复合物I的组成部分，复合物I是对线粒体氧化磷酸化和调节NADH / NAD +水平至关重要的核心酶复合物。

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《British Journal of Haematology》 |2013年第6期|共5页
作者
MorganM.A.; MarkusB.; HermkensM.; DammF.; ReinhardtD.; ZimmermannM.; TholF.; BunkeT.; BogoevaD.; ReuterC.W.M.; deHaasV.; vandenHeuvel-EibrinkM.M.; ZwaanC.M.; ReinhardtK.;
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正文语种 eng
中图分类血液及淋巴系疾病;
关键词
Mitochondria; mitochondrially encoded NADH dehydrogenase 4; Paediatric acute myeloid leukaemia; SETDB2;

机译：线粒体;线粒体编码的NADH脱氢酶4;儿科急性髓性白血病;SETDB2;

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1. NADH dehydrogenase subunit 4 variant sequences in childhood acute myeloid leukaemia [J] . MorganM.A., MarkusB., HermkensM., British Journal of Haematology . 2013,第6期

机译：儿童急性髓性白血病中NADH脱氢酶亚基4变异序列
2. Ancient Ascaris DNA Sequences of Cytochrome B, Cytochrome C Oxidase Subunit 1, NADH Dehydrogenase Subunit 1, and Internal Transcribed Spacer 1 Genes from Korean Joseon Mummy Feces [J] . Hong Jong Ha, Oh Chang Seok, Seo Min, Journal of Parasitology . 2017,第6期

机译：细胞色素B，细胞色素C氧化酶亚基1，NADH脱氢酶亚基1和来自韩国Joseon Mummy Mummy Feeces的内部转录间隔物1基因的古代蛔虫DNA序列
3. Contribution of NADH dehydrogenase subunit I and cytochrome C oxidase subunit I sequences toward identifying a case of human coenuriasis in France. [J] . Collomb J, Machouart M, Biava MF, Journal of Parasitology . 2007,第4期

机译：在法国，NADH脱氢酶亚基I和细胞色素C氧化酶亚基I序列对鉴定人类遗尿症的贡献。
4. WGAN Latent Space Embeddings for Blast Identification in Childhood Acute Myeloid Leukaemia [C] . Roxane Licandro, Thomas Schlegl, Michael Reiter, International Conference on Pattern Recognition . 2018

机译：WGAN潜在空间嵌入在儿童急性髓性白血病中的爆炸鉴定。
5. A Peptide Comprising the Src-Interacting Domain of NADH Dehydrogenase Subunit 2 Alleviates Complete Freund's Adjuvant-Induced Allodynia in Rats. [D] . Barszczyk, Andrew. 2010

机译：包含NADH脱氢酶亚基2 Src相互作用域的肽减轻大鼠完全弗氏佐剂诱导的异常性疼痛。
6. cDNA-derived amino acid sequence of the NADH-binding 51-kDa subunit of the bovine respiratory NADH dehydrogenase reveals striking similarities to a bacterial NAD(+)-reducing hydrogenase. [O] . S D Patel, R Aebersold, G Attardi 1991

机译：牛呼吸NADH脱氢酶的NADH结合51-kDa亚基的cDNA衍生的氨基酸序列揭示了与细菌NAD（+）还原氢酶的惊人相似之处。
7. cDNA-derived amino acid sequence of the NADH-binding 51-kDa subunit of the bovine respiratory NADH dehydrogenase reveals striking similarities to a bacterial NAD(+)-reducing hydrogenase [O] . Patel Salil D., Aebersold Ruedi, Attardi Giuseppe 1991

机译：牛呼吸NADH脱氢酶的NADH结合51-kDa亚基的cDNA衍生的氨基酸序列揭示了与细菌NAD（+）还原氢化酶的惊人相似之处

NADH dehydrogenase subunit 4 variant sequences in childhood acute myeloid leukaemia

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