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首页> 外文期刊>Internal medicine journal >Nocturnal hypoxia in motor neuron disease is not predicted by standard respiratory function tests.
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Nocturnal hypoxia in motor neuron disease is not predicted by standard respiratory function tests.

机译：标准呼吸功能测试不能预测运动神经元疾病的夜间缺氧。

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BACKGROUND: With increasing awareness of motor neuron disease (MND) in Australia, the approach to respiratory management of patients with this disease will more commonly face the respiratory physician. AIM: The aim of this study was to determine if standard respiratory function tests could determine the presence of nocturnal hypoxia (NH) in patients with MND. METHODS: Respiratory function tests were used to examine daytime respiratory function, and sleep studies were used to detect NH in 16 consecutive patients with MND and in 9 healthy control subjects. Demographic data, clinical parameters, respiratory function tests and sleep studies were obtained. Statistical analyses were carried out using t-tests and anova, where appropriate. RESULTS: NH was detected in 50% of patients with MND, with no hypoxic events detected in the control group. Standard respiratory function tests were not able to predict the presence of NH. CONCLUSION: There was no correlation between respiratory function tests and NH. This study emphasizes the inability of standard respiratory function tests to predict NH that may arise early in the course of MND.
机译：背景：随着澳大利亚对运动神经元疾病（MND）的认识的提高，患有这种疾病的患者进行呼吸管理的方法将更常见于呼吸内科医生。目的：本研究的目的是确定标准的呼吸功能检查是否可以确定MND患者是否存在夜间缺氧（NH）。方法：使用呼吸功能测试来检查白天的呼吸功能，并使用睡眠研究来检测连续16例MND患者和9例健康对照者的NH。获得了人口统计学数据，临床参数，呼吸功能测试和睡眠研究。在适当的情况下，使用t检验和方差分析进行统计分析。结果：50％的MND患者中检测到NH，而对照组中未检测到低氧事件。标准呼吸功能测试不能预测NH的存在。结论：呼吸功能检查与NH之间无相关性。这项研究强调了标准呼吸功能测试无法预测MND早期可能出现的NH。

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