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首页> 外文期刊>International Journal of Epidemiology: Official Journal of the International Epidemiological Association >Social disadvantages in childhood and risk of all-cause death and cardiovascular disease in later life: a comparison of historical and retrospective childhood information.
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Social disadvantages in childhood and risk of all-cause death and cardiovascular disease in later life: a comparison of historical and retrospective childhood information.

机译：童年时期的社会不利因素以及晚年造成全因死亡和心血管疾病的风险：历史和回顾性儿童时期信息的比较。

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BACKGROUND: Childhood socioeconomic circumstances have been shown to contribute to adult mortality. The purpose of this study was to compare the association between objective historical records and recalled questionnaire-based information on childhood socioeconomic position (SEP) with regard to cardiovascular and all-cause mortality. METHODS: We examined the association between a socially disadvantaged childhood and all-cause mortality, cardiovascular disease (CVD) mortality, coronary heart disease (CHD) mortality, and acute coronary events among male participants in the Kuopio Ischemic Heart Disease (KIHD) Risk Factor Study, a population-based cohort study in eastern Finland with follow-up until 2002. The historical data on childhood factors were collected from school health records (n = 698), mainly from the 1930s to the 1950s. Recall data on socioeconomic conditions in childhood were obtained from the baseline examinations of the KIHD cohort (n = 2,682) in 1984-89. RESULTS: According to original school health records the men who were socially disadvantaged in childhood had a 1.41-fold (95% confidence interval 1.01-1.97) age-adjusted and examination-year-adjusted risk of all-cause death, a 1.32-fold (0.83-2.11) risk of CVD death, a 1.48-fold (0.85-2.57) risk of CHD death, and a 1.50-fold (1.02-2.20) risk of acute coronary events. After adjustment for biological and behavioural risk factors and for the SEP in adulthood the association was attenuated in all-cause death but did not change in CVD death, CHD death, and acute coronary events. On the contrary, the questionnaire-based recalled childhood data on childhood SEP showed no associations with mortality or acute coronary events. CONCLUSIONS: With regard to adult mortality, the use of historical records concerning hygiene and living conditions collected in childhood may either provide more accurate measures of early-life socioeconomic conditions or capture more relevant aspects of childhood socioeconomic disadvantage than retrospective recall data.
机译：背景：已证明儿童的社会经济状况会导致成年人死亡。这项研究的目的是比较客观历史记录与基于回忆调查表的有关儿童心血管疾病和全因死亡率的儿童社会经济地位（SEP）信息之间的关联。方法：我们检查了社会弱势儿童与全因死亡率，心血管疾病（CVD）死亡率，冠心病（CHD）死亡率和库奥皮奥缺血性心脏病（KIHD）危险因素男性参与者之间的关联。该研究是一项在芬兰东部进行的基于人群的队列研究，随访至2002年。有关儿童因素的历史数据主要来自1930年代至1950年代的学校健康记录（n = 698）。回顾儿童时期的社会经济状况的数据是从1984-89年KIHD队列（n = 2,682）的基线检查中获得的。结果：根据学校的原始健康记录，在童年时期处于社会不利地位的男人的年龄调整后和经检查年调整后的全因死亡风险为1.41倍（95％置信区间1.01-1.97），为1.32倍CVD死亡的风险为（0.83-2.11），CHD死亡的风险为1.48倍（0.85-2.57），急性冠脉事件的风险为1.50倍（1.02-2.20）。在对生物学和行为危险因素以及成年期的SEP进行调整后，该协会的全因死亡减轻了，但CVD死亡，CHD死亡和急性冠状动脉事件并未改变。相反，基于问卷的回顾性童年SEP童年数据显示与死亡率或急性冠状动脉事件无关联。结论：关于成年人死亡率，与回顾性回忆数据相比，使用有关儿童时期卫生和生活条件的历史记录可能提供更准确的早期社会经济状况衡量指标，或捕获儿童社会经济劣势的更多相关方面。

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