HLA and eye disease: a synopsis.

Goverdhan SV; Lotery AJ; Howell WM

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HLA and eye disease: a synopsis.

机译：HLA和眼病：简介。

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Human leukocyte antigen (HLA) gene products have been implicated in the pathogenesis of an increasing number of eye diseases, mainly inflammatory in nature. This perspective reviews the current hypotheses for why HLA polymorphisms are associated with specific eye diseases. Statistical problems in studies involving HLA associations are discussed, and possible solutions outlined. The relevance of HLA testing in routine ophthalmic practice, its practical and cost implications is also assessed.

机译：人类白细胞抗原（HLA）基因产物与越来越多的眼部疾病（主要是炎症性疾病）的发病机理有关。这种观点回顾了为什么HLA多态性与特定的眼部疾病有关的当前假说。讨论了涉及HLA关联的研究中的统计问题，并概述了可能的解决方案。还评估了HLA测试在常规眼科实践中的相关性，其实践意义和成本影响。

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《International journal of immunogenetics》 |2005年第6期|共10页
作者
Goverdhan SV; Lotery AJ; Howell WM;
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正文语种 eng
中图分类基础医学;
关键词
Eye Diseases; HLA Antigens; Polymorphism; Genetic; 眼疾病; HLA抗原;

机译：Eye Diseases;HLA Antigens;Polymorphism;Genetic;眼疾病;HLA抗原;

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1. HLA and eye disease: a synopsis. [J] . Goverdhan SV, Lotery AJ, Howell WM International journal of immunogenetics . 2005,第6期

机译：HLA和眼病：简介。
2. Conjunctival epithelial cell HLA-DR expression and association with signs and symptoms of Dry Eye Disease (DED) in the 'Dry Eye Assessment and Management' (DREAM (c)) Study. [J] . Roy Neeta S., Wei Yi, Kuklinski Eric, Investigative ophthalmology & visual science . 2018,第9期

机译：结膜上皮细胞HLA-DR表达和与干眼症（DED）的症状和症状在“干眼症评估和管理”中的表达和症状（梦（C））研究。
3. Correlation Between the Inflammatory Marker HLA-DR and Signs and Symptoms in Moderate to Severe Dry Eye Disease [J] . Fran?§oise Brignole-Baudouin, Luisa Riancho, Dahlia Ismail, Investigative ophthalmology & visual science . 2017,第4期

机译：炎症标志物HLA-DR与中度至重度干眼症的体征和症状之间的相关性
4. Association of HLA-B*5101 and Characteristics of Patients with Behcet's Disease in China using HLA-B51 OligoChip [C] . Sun Yuping, Shen Hong, Liu Jie, International Forum on Progress on Post-Genome Technologies(5'IFPT); 20070910-11; Suzhou(CN) . 2007

机译：HLA-B51 OligoChip与HLA-B * 5101和中国白塞氏病患者特征的关联
5. Impression cytology with HLA-DR quanitification for the evaluation of Dry Eye Disease [D] . Ghobrial, Christine Nader 2008

机译：HLA-DR定量印象细胞学评估干眼病
6. Conjunctival Inflammatory Gene Expression Profiling in Dry Eye Disease: Correlations With HLA-DRA and HLA-DRB1 [O] . Karima Kessal, Hong Liang, Ghislaine Rabut, -1

机译：干眼病中结膜炎性基因表达谱分析：与HLA-DRA和HLA-DRB1的关系
7. Immunogenetic factors in inflammatory eye disease. influence of hla–b27 and alpha1-antitrypsin phenotypes on disease expression [O] . Denis Wakefield, Samuel N. Breit, Peggy Clark, 1982

机译：炎症眼病的免疫原因因素。 HLA-B27和Alpha1-Antrydsin表型对疾病表达的影响

HLA and eye disease: a synopsis.

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