Characterization of a novel HLA-B*40 allele, HLA-B*40:186:02, by cloning and sequencing

Wang W. Y.; Zhang W.; Cai J. H.; Zhu F. M.; Tian W.

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Characterization of a novel HLA-B40 allele, HLA-B40:186:02, by cloning and sequencing

机译：通过克隆和测序表征新型HLA-B * 40等位基因HLA-B * 40：186：02

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A novel HLA-B*40 variant, HLA-B*40:186:02, has been identified by cloning and sequencing in a southern Chinese Han population. Aligned with HLA-B*40:01:01, HLA-B*40:186:02 has a nonsynonymous cytosine mutation at nucleotide position 165 in exon 2, leading to amino acid change from glycine to arginine at codon 56. It differs from HLA-B*40:186:01 by a synonymous change (adenine to cytosine) at position 165 in exon 2.

机译：通过在中国南方汉族人群中的克隆和测序，鉴定了一种新型的HLA-B * 40变体HLA-B * 40：186：02。与HLA-B * 40：01：01对齐的HLA-B * 40：186：02在外显子2的核苷酸位置165处具有非同义的胞嘧啶突变，导致第56位密码子的氨基酸由甘氨酸变为精氨酸。 HLA-B * 40：186：01由外显子2中第165位的同义词变化（腺嘌呤变为胞嘧啶）引起。

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《International journal of immunogenetics》 |2016年第4期|共2页
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Wang W. Y.; Zhang W.; Cai J. H.; Zhu F. M.; Tian W.;
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正文语种 eng
中图分类免疫性疾病;
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1. Characterization of a novel HLA-B*40 allele, HLA-B*40:186:02, by cloning and sequencing [J] . Wang W. Y., Zhang W., Cai J. H., International journal of immunogenetics . 2016,第4期

机译：通过克隆和测序表征新型HLA-B * 40等位基因HLA-B * 40：186：02
2. HLA-B*40:02:18, a new HLA-B*40 allele [J] . KoS.-Y., OhH.-B., JunJ.-H., Tissue antigens. . 2014,第6期

机译：HLA-B * 40:02:18，一个新的HLA-B * 40等位基因
3. Sequence-based typing identified a new HLA-B*40 allele, HLA-B*40:124:02 [J] . LiD.-M., ShanX.-Y., NiL., Tissue antigens. . 2013,第6期

机译：基于序列的分型确定了新的HLA-B * 40等位基因HLA-B * 40：124：02
4. Molecular docking analysis of 2009-H1N1 and 2004-H5N1 influenza virus HLA-B*4405-restricted HA epitope candidates: implications for TCR cross-recognition and vaccine development [C] . Chinh TT Su, Christian Schonbach, Chee-Keong Kwoh Asia-Pacific Bioinformatics Conference . 2013

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5. Identification, cloning, sequencing, and characterization of a proposed lactacin B enhancer protein and partial characterization of the Lactobacillus delbrueckii ssp. lactis ATCC 4797 genome by shotgun cloning and random sequencing. [D] . Ulrich, Ricky Lee. 1999

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6. Substantial Influence of ERAP2 on the HLA-B*40:02 Peptidome: Implications for HLA-B*27-Negative Ankylosing Spondylitis [O] . Elena Lorente, Jennifer Redondo-Antón, Adrian Martín-Esteban, 2019

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7. Identification of the new HLA-B*44:02:45, DQB1*02:85, DQB1*06:210, DRB1*01:01:30 alleles by monoallelic Sanger sequencing [O] . Elena V. Kuzmich, Alexander L. Alyanskiy, Svetlana S. Tyapushkina, 2018

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Characterization of a novel HLA-B*40 allele, HLA-B*40:186:02, by cloning and sequencing

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Characterization of a novel HLA-B40 allele, HLA-B40:186:02, by cloning and sequencing