...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Infectious diseases in obstetrics and gynecology >The in vitro activity of vaginal Lactobacillus with probiotic properties against Candida.
【24h】

The in vitro activity of vaginal Lactobacillus with probiotic properties against Candida.

机译：具有益生菌性质的阴道乳杆菌对念珠菌的体外活性。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Lactobacilli, the predominant vaginal microorganisms in healthy premenopausal women, control other members of the vaginal microflora and thus protect against bacterial vaginosis and urinary tract infections. It has been claimed that some lactobacilli are also protective against Candida vaginitis. Little is known, however, about the mechanisms by which these lactobacilli can control vaginal populations of Candida and prevent vaginitis. To address this question, vaginal Lactobacillus strains with known antagonistic properties against bacteria were tested for their cell surface properties, adhesion to vaginal cell lines in vitro and antagonistic activities against Candida. A small proportion of the lactobacilli tested adhered strongly to cultured vaginal epithelial cells and inhibited growth of Candida albicans but not of C. pseudotropicalis. This anticandidal activity was in some Lactobacillus strains related to hydrogen peroxide (H2O2) production, but catalase treatment did not suppress this activity inother Lactobacillus strains, suggesting alternative mechanism(s). Moreover, tested vaginal Candida strains were resistant to relatively high concentrations of H2O2 that markedly exceeded those produced by even the most active Lactobacillus strains.
机译：乳杆菌是健康的绝经前妇女的主要阴道微生物，它控制着阴道微生物群的其他成员，因此可以防止细菌性阴道病和尿路感染。据称，某些乳酸菌也可预防念珠菌性阴道炎。然而，关于这些乳杆菌可控制念珠菌的阴道种群并预防阴道炎的机制知之甚少。为了解决这个问题，测试了具有已知对细菌拮抗特性的阴道乳酸杆菌菌株的细胞表面特性，体外对阴道细胞系的粘附性以及对念珠菌的拮抗活性。所测试的一小部分乳杆菌强烈粘附于培养的阴道上皮细胞，并抑制白色念珠菌的生长，但不能抑制拟热带假丝酵母的生长。此抗候选活性在某些与过氧化氢（H2O2）产生有关的乳酸杆菌菌株中，但过氧化氢酶处理并未在其他乳酸杆菌菌株中抑制该活性，表明存在其他机制。此外，经测试的阴道念珠菌菌株对较高浓度的H2O2具有抗性，该浓度甚至超过了活性最高的乳酸杆菌菌株所产生的浓度。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号