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首页> 外文期刊>International review of psychiatry >Validity and clinical utility of the current operational characterization of major depression
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Validity and clinical utility of the current operational characterization of major depression

机译：当前对重度抑郁症的手术特征的有效性和临床实用性

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The operational definition of major depression has remained more or less the same in the past 40 years. An appraisal of currently available research data leads to the conclusion that further evidence is needed about (1) where to fix the boundary between cases and non-cases in order to improve the clinical utility of the diagnosis, (2) the validity and clinical utility of the construct of melancholia as a qualitatively distinct subtype of depression, and (3) the validity and clinical utility of a 'contextual' exclusion criterion. Furthermore, we need a more precise description of individual depressive symptoms, an exploration of the predictive value of these symptoms and of clusters of them, especially concerning clinical outcome and treatment response, and a clearer operationalization of the impairment criterion.
机译：在过去的40年中，重度抑郁症的操作定义大致相同。对当前可用研究数据的评估得出以下结论：需要进一步的证据，以了解（1）固定病例与非病例之间的界限以提高诊断的临床效用，（2）有效性和临床效用抑郁症在质量上与抑郁症不同，是一种忧郁症;（3）“情境”排除标准的有效性和临床实用性。此外，我们需要对个体抑郁症状进行更精确的描述，对这些症状及其群集的预测价值进行探索，尤其是在临床结果和治疗反应方面，以及更清晰地实施损伤标准。

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