• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>International journal of obstetric anesthesia >Maternal haemodynamics at elective caesarean section: a randomised comparison of oxytocin 5-unit bolus and placebo infusion with oxytocin 5-unit bolus and 30-unit infusion.
【24h】

Maternal haemodynamics at elective caesarean section: a randomised comparison of oxytocin 5-unit bolus and placebo infusion with oxytocin 5-unit bolus and 30-unit infusion.

机译：孕妇剖腹产的血流动力学：催产素5单位推注和安慰剂输注与催产素5单位推注和30单位输注的随机比较。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

BACKGROUND: Rapid intravenous injection of oxytocin is associated with marked hypotension secondary to decreased venous return. Reductions in dose and rate of bolus administration have reduced the incidence of cardiovascular side effects, but no study has yet investigated cardiovascular stability when oxytocin is infused for several hours after delivery. This study compared maternal haemodynamics during a 4-h 30-unit oxytocin infusion and during a placebo infusion following caesarean section. METHODS: Women booked for elective caesarean section were randomised to receive either oxytocin 5-unit bolus and placebo infusion or oxytocin 5-unit bolus and oxytocin 30-unit infusion. Before, during and for 4 h after surgery electrocardiogram, oxygen saturation, systolic and diastolic pressure and heart rate were monitored non-invasively and cardiac index (CI), left ventricular work index (LVWi) and systemic vascular resistance index (SVRi) by thoracic bioimpedance. RESULTS: A total of 74 women agreed to haemodynamic measurements. Heart rate, systolic and diastolic pressure, CI, LCWi and SVRi all fell following the onset of spinal anaesthesia, and, with the exception of SVRi, continued to decrease throughout surgery. After delivery of the baby, slow injection of oxytocin 5 units was associated with a temporary rise in CI, LCWi and heart rate, a decrease in SVRi and no change in systolic or diastolic pressure. Thereafter, haemodynamic measures returned to normal over 60 min with no adverse effects apparent from the additional oxytocin infusion. CONCLUSIONS: An additional oxytocin infusion at elective caesarean section did not adversely affect maternal haemodynamics either during or after surgery.
机译：背景：催产素的快速静脉注射与继发于静脉回流减少的明显低血压有关。推注剂量和剂量减少可降低心血管副作用的发生率，但尚无研究研究在分娩后数小时内注入催产素时的心血管稳定性。这项研究比较了剖宫产术后4小时30单位催产素输注期间和安慰剂输注期间孕妇的血流动力学。方法：将预订剖腹产的妇女随机接受催产素5单位推注和安慰剂输注或催产素5单位推注和催产素30单位推注。术前，术中和术后4 h，无创地监测血氧饱和度，收缩压和舒张压以及心率，并通过胸腔监测心脏指数（CI），左心室工作指数（LVWi）和全身血管阻力指数（SVRi）生物阻抗。结果：共有74名妇女同意进行血流动力学测量。脊髓麻醉开始后，心率，收缩压和舒张压，CI，LCWi和SVRi均下降，并且除SVRi外，在整个手术过程中持续下降。婴儿分娩后，缓慢注射催产素5单位与CI，LCWi和心率的暂时升高，SVRi的降低以及收缩压或舒张压的改变无关。此后，血流动力学指标在60分钟内恢复正常，而从其他催产素输注中未见明显不良反应。结论：选择性剖宫产术中追加催产素输注不会对手术期间或术后母亲的血流动力学产生不利影响。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号