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Sources of error in lung densitometry with CT.

机译:CT肺密度测定的误差来源。

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RATIONALE AND OBJECTIVES: To determine and analyze the most important error sources in lung CT densitometry in vivo. METHODS: The authors examined the influences of CT acquisition errors, physiologic changes, and image segmentation errors on lung densitometry. Among others, spatial dependency and long-term reproducibility of the density measurements of blood and air were examined over a period of 4 years in a group of 28 patients with pulmonary emphysema. These results were related to the measured lung densities in this group. RESULTS: The density measurement of blood and air is strongly dependent on the position in the thorax. Despite full-scanner calibrations, x-ray tube replacement can induce a significant increase in measured blood density. CONCLUSIONS: A change in a lung density parameter over time can actually be the result of tube replacement or changing blood density. A simple postprocessing technique can correct for these changes.
机译:理由和目的:确定和分析体内肺部CT密度测定法中最重要的错误来源。方法:作者检查了CT采集误差,生理变化和图像分割误差对肺密度的影响。其中,在一组28例肺气肿患者中,在4年的时间内检查了血液和空气密度测量值的空间依赖性和长期可重复性。这些结果与该组中测得的肺密度有关。结果:血液和空气的密度测量强烈取决于胸腔中的位置。尽管进行了全扫描仪校准,但更换X射线管仍会导致所测得的血液密度显着增加。结论:肺密度参数随时间的变化实际上可能是管更换或血液密度变化的结果。一种简单的后处理技术可以纠正这些更改。

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