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首页> 外文期刊>Irish medical journal. >Percutaneous vertebroplasty in painful osteoporotic vertebral collapse: a safe treatment option for intractable pain.
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Percutaneous vertebroplasty in painful osteoporotic vertebral collapse: a safe treatment option for intractable pain.

机译：经皮椎体成形术治疗疼痛性骨质疏松性椎体塌陷：治疗顽固性疼痛的安全选择。

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摘要

Osteoporois is a rapidly growing condition in Ireland and the Western world and is associated with significant morbidity, primarily due to pain and immobility. In the past, pain from osteoporotic vertebral collapse could only be treated by limited means including pain killers and external supports. In recent years, percutaneous vertebroplasty of painful osteoporotic vertebral collapse has made a significant contribution to treating such patients. However its role remains largely unknown to many health care professionals denying potential access of patients with often severe symptoms to a potential relief of their pain. Osteoporosis is a condition of decreased bone mass resulting from a combination of inadequate accumulation of bone mass and rapid resorption after menopause1. Criteria for diagnosis have been established by World Health Organisation and are based on comparing the bone mineral density (BMD) of a patient to that of a typically young female. BMD values 2.5 standard deviations below the mean are deemed osteoporotic and are measured by densitometry. Routine hormonal replacement treatment is no longer first line due to ongoing concerns regarding adverse effects identified in long-term follow- up studies. Primary treatment is based on correction of underlying metabolic abnormalities with provision of calcium and vitamin D supplementation combined with bisphosphonates or calcitonin, or both.
机译：骨质疏松症在爱尔兰和西方世界是一种快速发展的疾病，与主要由于疼痛和行动不便引起的高发病率有关。过去，只能通过有限的手段（包括止痛药和外部支持物）来治疗骨质疏松性椎体塌陷引起的疼痛。近年来，痛苦的骨质疏松性椎体塌陷的经皮椎体成形术对治疗此类患者做出了重大贡献。然而，它的作用对于许多医疗保健专业人员来说仍然基本上是未知的，因为他们否认具有严重症状的患者可能缓解疼痛的潜在途径。骨质疏松是由于骨量堆积不足和更年期后快速吸收而导致骨量减少的一种情况。世界卫生组织已经建立了诊断标准，该标准基于将患者的骨矿物质密度（BMD）与典型的年轻女性的骨矿物质密度进行比较。 BMD值低于平均值的2.5个标准差被认为是骨质疏松症，并通过光密度法测量。由于对长期随访研究中发现的不良反应的持续关注，常规的激素替代治疗不再是一线治疗。初级治疗的基础是纠正潜在的代谢异常，方法是补充钙和维生素D，并补充双膦酸盐或降钙素，或两者同时进行。

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