• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Electroanalysis >Electroaddressable selective functionalization of electrode arrays: Catalytic NADH detection using aryl diazonium modified gold electrodes
【24h】

Electroaddressable selective functionalization of electrode arrays: Catalytic NADH detection using aryl diazonium modified gold electrodes

机译：电极阵列的可电寻址选择性功能化：使用芳基重氮修饰的金电极进行催化NADH检测

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

We report the application of 4-nitrophenyl diazonium modified electrodes towards the electrochemical detection of NADH. Selective activation of individual electrodes on a 5 element array by electro-addressable conversion of nitro groups to amines and subsequent EDC/NHS crosslinking to the NADH oxidant, pyrroloquinoline quinone (PQQ), is demonstrated. Inactivated electrodes retained nitro functionality and were protected against non-specific adsorption and mild chemical reactions. Electrodeposition conditions were used to control nitrophenyl film thickness and showed that while increased film thickness leads to greater functionalization density of PQQ, it also results in decreased electron transfer kinetics. The electrodeposition protocol can therefore serve as a method to control electrode functionalization density and film electron transfer kinetics. We believe this simple technique for selective electrode functionalization may facilitate the development of next generation multianalyte electrochemical sensors.
机译：我们报告了4-硝基苯基重氮修饰电极在NADH电化学检测中的应用。通过将硝基电转化为胺，然后将EDC / NHS交联至NADH氧化剂吡咯并喹啉醌（PQQ），证明了5元素阵列上各个电极的选择性活化。灭活的电极保留了硝基功能，可以防止非特异性吸附和轻微的化学反应。电沉积条件用于控制硝基苯基膜的厚度，结果表明，虽然膜厚度的增加会导致PQQ的官能化密度更高，但也会导致电子传递动力学下降。因此，电沉积规程可以用作控制电极功能化密度和薄膜电子转移动力学的方法。我们相信这种用于选择性电极功能化的简单技术可能会促进下一代多分析物电化学传感器的开发。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号