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Signal enhancement of electrochemical biomemory device composed of recombinant azurin/gold nanoparticle

机译:重组天青素/金纳米粒子组成的电化学生物记忆装置的信号增强

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摘要

A signal-enhanced biomemory device was developed by introducing cysteine-modified azurin/gold nanoparticle (GNP) heterolayers. The proposed recombinant azurin/GNP heterolayers provided an enhanced electron transfer between recombinant azurin/GNP and the Au surface, which stored the charges in the fabricated heterolayer. The fabricated recombinant azurin/GNP heterolayers was investigated by atomic force microscopy (AFM) and surface plasmon resonance (SPR) spectroscopy. Cyclic voltammetry (CV) was performed to examine the current signal-amplified electrochemical property. In this analysis, the recombinant azurin/GNP heterolayers produced current that was 5 times greater than the recombinant azurin monolayer. These redox potentials were then used to obtain the 'write step' and 'erase step'. Using these parameters, the biomemory function of the device was verified by chronoamperometry (CA).
机译:通过引入半胱氨酸修饰的天青蛋白/金纳米颗粒(GNP)杂层,开发了一种信号增强型生物记忆设备。拟议的重组天青蛋白/ GNP杂层在重组天青蛋白/ GNP和Au表面之间提供了增强的电子转移,从而将电荷存储在制造的杂层中。通过原子力显微镜(AFM)和表面等离子体共振(SPR)光谱研究了制备的重组天青蛋白/ GNP异质层。进行循环伏安法(CV)来检查电流信号放大的电化学性能。在此分析中,重组天青蛋白/ GNP杂层产生的电流是重组天青蛋白单层的5倍。然后将这些氧化还原电位用于获得“写入步骤”和“擦除步骤”。使用这些参数,通过计时电流法(CA)验证了设备的生物记忆功能。

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