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首页> 外文期刊>Equine Veterinary Education >Pulmonary and hepatic eosinophilic granulomas and epistaxis in a horse suggestive of multi-systemic eosinophilic epitheliotropic disease
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Pulmonary and hepatic eosinophilic granulomas and epistaxis in a horse suggestive of multi-systemic eosinophilic epitheliotropic disease

机译：一匹马的肺和肝嗜酸性肉芽肿和鼻epi提示多系统性嗜酸性上皮性疾病

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摘要

Multi-systemic eosinophilic epitheliotropic disease (MEED) is a relatively uncommon disease characterised by eosinophilic infiltration of more than one organ system, with the skin and gastrointestinal tract most commonly affected. This case report describes a gelding that presented for weight loss, increased respiratory rate and effort and chronic intermittent epistaxis. During post mortem examination diffuse eosinophilic granulomatous lesions were identified in the lung and liver, leading to a diagnosis of MEED. Veno-occlusive pulmonary remodelling was also discovered, believed to be the cause of the chronic epistaxis and a result of the pulmonary fibrosis and eosinophilic granulomas.
机译：多系统性嗜酸性粒细胞增生性疾病（MEED）是一种相对罕见的疾病，其特征是嗜酸性细胞浸润了多个器官系统，其中皮肤和胃肠道最常见。该病例报告描述了一种weight脂，可减轻体重，增加呼吸频率和精力，并具有慢性间歇性鼻epi。验尸期间，在肺和肝中发现了弥漫性嗜酸性肉芽肿性病变，从而诊断出MEED。还发现了闭塞性肺重塑，被认为是慢性鼻axis的原因，也是肺纤维化和嗜酸性肉芽肿的结果。

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