• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Esophagus >Salvage lymphadenectomy without esophagectomy is an option for recurrent or residual lymph nodes after definitive chemoradiotherapy for esophageal cancer
【24h】

Salvage lymphadenectomy without esophagectomy is an option for recurrent or residual lymph nodes after definitive chemoradiotherapy for esophageal cancer

机译：食管癌明确放化疗后复发或残留淋巴结的选择是不进行食管切除术的抢救淋巴结清扫术

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Pwposes The aim of this study was to determine the prognostic factors in salvage surgery following definitive chemoradiotherapy (dCRT) for esophageal cancer. Methods We retrospectively reviewed twenty-five patients who underwent salvage surgery from 1986 to 2011 at Kurume University Hospital. Results Esophagectomy was adopted for 20 patients, while lymphadenectomy alone without esophagectomy was adopted for the other 5 patients. Univariate analysis found that age, response to initial treatment, presence of residual tumor, pT after salvage surgery, and severe complications were each significantly correlated with overall survival after salvage surgery. The type of surgery (esophagectomy vs lymphadenectomy) and presence of residual tumor (R) were each determined to be an independent prognostic factor by the multivariate analysis. Namely, the prognosis after R0 resection was better than that after Rl/2 resection (HR 18.050, p < 0.0001), and the prognosis after, salvage lymphadenectomy was better than that after salvage esophagectomy (HR 5.091, p = 0.0086). Conclusions Salvage lymphadenectomy without esophagectomy is suggested to be an option for patients having recurrent or residual lymph nodes without any other recurrence or residual tumor after dCRT for esophageal cancer.
机译：目的本研究的目的是确定针对食管癌的定性放化疗后的挽救手术的预后因素。方法回顾性分析1986年至2011年在久留米大学医院接受挽救手术的25例患者。结果20例患者接受了食管切除术，其余5例仅采用了不进行食管切除术的淋巴结清扫术。单因素分析发现，年龄，抢救手术后残余肿瘤的存在，抢救手术后的pT以及严重并发症均与抢救手术后的总体生存率显着相关。通过多变量分析，手术类型（食管切除术与淋巴结清扫术）和是否存在残余肿瘤（R）被确定为独立的预后因素。即，R0切除后的预后好于R1 / 2切除后（HR 18.050，p <0.0001），而挽救性淋巴结清扫术的预后要优于挽救食管切除术的预后（HR 5.091，p = 0.0086）。结论dCRT后食管癌术后复发或残留淋巴结无其他复发或残留肿瘤的患者，建议行挽救性淋巴结清扫术而不进行食管切除术。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号