Rituximab in subacute sclerosing panencephalitis, Titomanlio et al., 2007;ll:43-5

Luigi Titomanlio; Najla Soyah; Philippe Evrard

首页> 外文期刊>European journal of paediatric neurology: EJPN : official journal of the European Paediatric Neurology Society >Rituximab in subacute sclerosing panencephalitis, Titomanlio et al., 2007;ll:43-5

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Rituximab in subacute sclerosing panencephalitis, Titomanlio et al., 2007;ll:43-5

机译：利妥昔单抗治疗亚急性硬化性全脑炎，Titomanlio等，2007; ll：43-5

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We thank Dr. Anlar for her comments. Her first remark concerns ethical aspects of Rituximab therapy in our patient. B-cells depletion might be risky, if we consider the usual course of the disease in immunosup-pressed patients. However, rituximab has a proven efficacy in several diseases, e.g., idiopathic thrombocytopenic purpura refractory to steroids and IVIg, without any major side effects.1 In these conditions, IVIg are usually prescribed for their immunomodulatory role. Therefore, the efficacy of IVIg is not sufficient to conclude that anti-CD20 agents could be dangerous in SSPE.

机译：我们感谢Anlar博士的评论。她的第一句话涉及我们患者的利妥昔单抗治疗的伦理方面。如果我们考虑免疫抑制患者的正常病程，则B细胞耗竭可能是有风险的。但是，利妥昔单抗在多种疾病中具有公认的功效，例如类固醇和IVIg难治的特发性血小板减少性紫癜，没有任何主要副作用.1在这些情况下，通常开具IVIg的免疫调节作用。因此，IVIg的功效不足以得出抗CD20药物在SSPE中可能是危险的结论。

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《European journal of paediatric neurology: EJPN : official journal of the European Paediatric Neurology Society》 |2007年第4期|共2页
作者
Luigi Titomanlio; Najla Soyah; Philippe Evrard;
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正文语种 eng
中图分类放射医学;
关键词
rituximab; Subacute Sclerosing Panencephalitis; g lt; 3gt; proven venom; 亚急性硬化全脑炎;

机译：rituximab;Subacute Sclerosing Panencephalitis;g 3;proven venom;亚急性硬化全脑炎;

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1. Rituximab in subacute sclerosing panencephalitis, Titomanlio et al., 2007;ll:43-5 [J] . Luigi Titomanlio, Najla Soyah, Philippe Evrard European journal of paediatric neurology: EJPN : official journal of the European Paediatric Neurology Society . 2007,第4期

机译：利妥昔单抗治疗亚急性硬化性全脑炎，Titomanlio等，2007; ll：43-5
2. Immunological studies of subacute measles encephalitis in ferrets: similarities to human subacute sclerosing panencephalitis. [J] . P D Mehta, H Thormar Journal of Clinical Microbiology . 1979,第5期

机译：雪貂亚急性麻疹脑炎的免疫学研究：与人类亚急性硬化性全脑炎的相似性。
3. Antiviral Effect of Favipiravir (T-705) against Measles and Subacute Sclerosing Panencephalitis Viruses [J] . Koichi Hashimoto, Kazuhide Suyama, Masatoki Sato, Japanese journal of infectious diseases . 2021,第2期

机译：Favipiravir（T-705）对麻疹和亚急性硬化脑膜炎病毒的抗病毒作用
4. Measles and Subacute Sclerosing Panecephalitis (SSPE) in the Last 18 Years in Romania [C] . D. Craiu, P. Avram, M. Craiu, International Conference on Diagnosis and Treatment in Pediatric Neurology . 2008

机译：在罗马尼亚的过去18年来的麻疹和亚急性硬化持续的平板炎（SSPE）
5. Measles and subacute sclerosing panencephalitis virus proteins: lack of antibodies to the M protein in patients with subacute sclerosing panencephalitis. [O] . W W Hall, R A Lamb, P W Choppin 1979

机译：麻疹和亚急性硬化性全脑炎病毒蛋白：亚急性硬化性全脑炎患者缺乏M蛋白抗体。
6. Measles and subacute sclerosing panencephalitis virus proteins: lack of antibodies to the M protein in patients with subacute sclerosing panencephalitis. [O] . Hall, W W, Lamb, R A, Choppin, P W 1979

机译：麻疹和亚急性硬化性全脑炎病毒蛋白：亚急性硬化性全脑炎患者缺乏M蛋白抗体。
7. Study of the Epidemiology of Subacute Sclerosing Panencephalitis (SSPE) and Maintenance of a National Registry of SSPE [R] . Dyken, P. R. 1983

机译：亚急性硬化性脑炎（sspE）流行病学研究及国家sspE登记处的维护

Rituximab in subacute sclerosing panencephalitis, Titomanlio et al., 2007;ll:43-5

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