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首页> 外文期刊>European journal of paediatric neurology: EJPN : official journal of the European Paediatric Neurology Society >Performance on Wechsler intelligence scales in children with Tourette syndrome.
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Performance on Wechsler intelligence scales in children with Tourette syndrome.

机译：抽动秽语综合征儿童的韦氏智力量表。

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摘要

BACKGROUND: There is some evidence that Tourette syndrome is associated with cognitive disabilities. AIMS: To examine the cognitive performance of a clinical cohort of children with Tourette syndrome. METHODS: 266 children with Tourette syndrome have been examined with Wechsler Intelligence Scales. The presence of the co-morbidities attention deficit hyperactivity disorder (ADHD) and obsessive-compulsive disorder (OCD) was assessed using validated diagnostic instruments. Eighty healthy controls matched a part of the TS cohort. RESULTS: The children with Tourette syndrome had a mean verbal IQ (VIQ) of 92.9, performance IQ (PIQ) of 87.1, and full-scale IQ (FSIQ) of 88.8. We found statistically significant higher PIQ and FSIQ in the control group compared with a matched TS cohort and a trend towards a higher VIQ among the healthy controls. There was a statistically significant influence of age at onset of tics on PIQ. The children with co-morbid OCD scored higher on FSIQ compared with the other groups. The children with co-morbid ADHD and OCD showed problems in motor tasks and speed tasks and the children with co-morbid ADHD showed attention deficits. CONCLUSIONS: Children with Tourette syndrome have lower IQ scores than the general population (but less than one standard deviation below) and our control group. Early onset of tics and the presence of co-morbidities might cause specific deficits on cognitive performance.
机译：背景：有证据表明，Tourette综合征与认知障碍有关。目的：研究图雷特综合症儿童临床队列的认知表现。方法：采用韦氏智力量表对266名患有抽动秽语综合征的儿童进行了检查。使用经验证的诊断工具评估并存的注意缺陷多动障碍（ADHD）和强迫症（OCD）的合并症。 80名健康对照者与TS队列的一部分相匹配。结果：图雷特综合症儿童的平均语言智商（VIQ）为92.9，表现智商（PIQ）为87.1，全面智商（FSIQ）为88.8。我们发现，与匹配的TS队列相比，对照组的PIQ和FSIQ具有统计学上的显着提高，而健康对照组的VIQ也有更高的趋势。抽搐发作的年龄对PIQ有统计学意义的影响。与其他组相比，患有合并症强迫症的儿童在FSIQ上得分更高。合并症多动症和强迫症的儿童在运动任务和速度任务中出现问题，合并症多动症的儿童表现出注意力缺陷。结论：抽动秽语综合征儿童的智商得分低于一般人群（但低于标准偏差一个）和我们的对照组。抽搐的早期发作和合并症的存在可能导致认知能力的特定缺陷。

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