Synthesis and study of antibacterial and antifungal activities of novel 1-(2-(benzoxazol-2-yl)ethoxy)- 2,6-diarylpiperidin-4-ones.

Ramalingan C; Balasubramanian S; Kabilan S; Vasudevan M

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Synthesis and study of antibacterial and antifungal activities of novel 1-(2-(benzoxazol-2-yl)ethoxy)- 2,6-diarylpiperidin-4-ones.

机译：新型1-（2-（苯并恶唑-2-基）乙氧基）-2,6-二芳基哌啶-4-酮的合成及抗菌活性研究。

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摘要

Some novel benzoxazolylethoxypiperidones have been synthesized and their antibacterial activity against streptococcus faecalis, bacillus subtilis, escherichia coli, staphylococcus aureus aand pseudomonas aeruginosa and antifungal activity against Candida-6, Candida albicans, Aspergillus niger, Candida-51 and Aspergillus flavus were evaluated. Compounds 37, 38 and 39 exerted potent in vitro antibacterial activity against Streptococcus faecalis while compounds 40 and 41 exhibited potent in vitro antifungal activity against Candida-51.

机译：合成了一些新颖的苯并恶唑基乙氧基哌啶酮，并评估了它们对粪链球菌，枯草芽孢杆菌，大肠杆菌，金黄色葡萄球菌和铜绿假单胞菌的抗菌活性以及对念珠菌6，白色念珠菌，黑曲霉和黑曲霉，念珠菌51的抗真菌活性。化合物37、38和39对粪便链球菌具有强大的体外抗菌活性，而化合物40和41对念珠菌51型则具有强大的体外抗菌活性。

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来源
《European Journal of Medicinal Chemistry: Chimie Therapeutique》 |2004年第6期|共7页
作者
Ramalingan C; Balasubramanian S; Kabilan S; Vasudevan M;
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正文语种 eng
中图分类基础医学;
关键词
novel; Candida; Synthesis; In Vitro; Enterococcus faecalis; 念珠菌属; 肠球菌; 粪;

机译：novel;Candida;Synthesis;In Vitro;Enterococcus faecalis;念珠菌属;肠球菌;粪;

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1. Synthesis and study of antibacterial and antifungal activities of novel 1-(2-(benzoxazol-2-yl)ethoxy)- 2,6-diarylpiperidin-4-ones. [J] . Ramalingan C, Balasubramanian S, Kabilan S, European Journal of Medicinal Chemistry: Chimie Therapeutique . 2004,第6期

机译：新型1-（2-（苯并恶唑-2-基）乙氧基）-2,6-二芳基哌啶-4-酮的合成及抗菌活性研究。
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Synthesis and study of antibacterial and antifungal activities of novel 1-(2-(benzoxazol-2-yl)ethoxy)- 2,6-diarylpiperidin-4-ones.

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