• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Immunology and allergy clinics of North America >Neuroendocrine effects of stress on immunity in the elderly: implications for inflammatory disease.
【24h】

Neuroendocrine effects of stress on immunity in the elderly: implications for inflammatory disease.

机译：压力对老年人免疫力的神经内分泌影响：对炎症性疾病的影响。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Age-related changes in immune function leave older adults at risk for a host of inflammatory diseases. Immune-mediated inflammatory processes are regulated by neuroendocrine hormones, including glucocorticoids, dehydroepiandrosterone, and the catecholamines, epinephrine, and norepinephrine. This regulation, however, becomes impaired in older adults in light of age-related changes in endocrine function. Chronic stress shows similarly harmful effects on neuroendocrine and immune function and may, therefore, combine with age to further increase disease risk in older adults. This article highlights evidence for the impact of age and stress on neuroendocrine regulation of inflammatory processes that may substantially increase risk for inflammatory disease at older ages.
机译：与年龄相关的免疫功能变化使老年人处于罹患多种炎性疾病的风险中。免疫介导的炎症过程受神经内分泌激素（包括糖皮质激素，脱氢表雄酮，儿茶酚胺，肾上腺素和去甲肾上腺素）的调节。然而，鉴于与年龄相关的内分泌功能变化，该调节在老年人中会受损。慢性应激对神经内分泌和免疫功能显示出类似的有害影响，因此可能与年龄结合，进一步增加老年人患疾病的风险。本文重点介绍了年龄和压力对炎症过程的神经内分泌调节的影响的证据，这可能会大大增加老年人发炎疾病的风险。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号