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首页> 外文期刊>European journal of epidemiology >Wine, beer or spirit drinking in relation to fatal and non-fatal cardiovascular events: A meta-analysis
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Wine, beer or spirit drinking in relation to fatal and non-fatal cardiovascular events: A meta-analysis

机译：与致命和非致命心血管事件相关的葡萄酒，啤酒或烈酒饮用：荟萃分析

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In previous studies evaluating whether different alcoholic beverages would protect against cardiovascular disease, a J-shaped relationship for increasing wine consumption and vascular risk was found; however a similar association for beer or spirits could not be established. An updated meta-analysis on the relationship between wine, beer or spirit consumption and vascular events was performed. Articles were retrieved through March 2011 by PubMed and EMBASE search and a weighed least-squares regression analysis pooled data derived from studies that gave quantitative estimation of the vascular risk associated with the alcoholic beverages. From 16 studies, evidence confirms a J-shaped relationship between wine intake and vascular risk. A significant maximal protection-average 31% (95% confidence interval (CI): 19-42%) was observed at 21 g/day of alcohol. Similarly, from 13 studies a J-shaped relationship was apparent for beer (maximal protection: 42% (95% CI: 19-58%) at 43 g/day of alcohol). From 12 studies reporting separate data on wine or beer consumption, two closely overlapping dose-response curves were obtained (maximal protection of 33% at 25 g/day of alcohol). This meta-analysis confirms the J-shaped association between wine consumption and vascular risk and provides, for the first time, evidence for a similar relationship between beer and vascular risk. In the meta-analysis of 10 studies on spirit consumption and vascular risk, no J-shaped relationship could be found.
机译：在先前的评估中，不同酒精饮料是否可以预防心血管疾病的研究发现，J型关系增加了葡萄酒的摄入量和血管风险。但是，无法建立类似的啤酒或烈酒协会。进行了有关葡萄酒，啤酒或烈酒消费与血管事件之间关系的最新荟萃分析。通过PubMed和EMBASE搜索检索到2011年3月的文章，并通过加权最小二乘回归分析汇总了研究得出的数据，这些研究给出了与酒精饮料相关的血管风险的定量估计。从16项研究中，证据证实葡萄酒摄入与血管风险之间呈J形关系。在每天21克酒精中观察到显着的最大保护平均水平31％（95％置信区间（CI）：19-42％）。同样，从13项研究中可以明显看出，啤酒呈J字形关系（在43克/天的酒精含量下，最大保护作用为42％（95％CI：19-58％））。从12个报告了有关葡萄酒或啤酒消费量的单独数据的研究中，获得了两条紧密重叠的剂量反应曲线（在25 g /天的酒精中最大保护33％）。这项荟萃分析证实了葡萄酒消费与血管风险之间呈J型关联，并首次为啤酒与血管风险之间的相似关系提供了证据。在10项关于精神消耗和血管风险的研究的荟萃分析中，没有发现J型关系。

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