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首页> 外文期刊>Experimental and therapeutic medicine >Posterior decompression and short segmental pedicle screw fixation combined with vertebroplasty for Kiimmell's disease with neurological deficits
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Posterior decompression and short segmental pedicle screw fixation combined with vertebroplasty for Kiimmell's disease with neurological deficits

机译：后减压联合短节段椎弓根螺钉内固定结合椎体成形术治疗伴有神经功能缺损的Kiimmell病

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The aim of this study was to investigate the treatment of Kummell's disease with neurological deficits and to determine whether intravertebral clefts are a pathognomonic sign of Kummell's disease. A total of 17 patients who had initially been diagnosed with Kummell's disease were admitted, one patient was excluded from this study. Posterior decompression and vertebroplasty for the affected vertebrae were conducted. Pedicle screw fixation and posterolateral bone grafts were performed one level above and one level below the affected vertebrae. Vertebral tissue was extracted for histopathological examination. The mean time of follow-up was 22 months (range, 18 to 42 months). The anterior and middle vertebral heights were measured on standing lateral radiographs prior to surgery, one day postoperatively and at final follow-up. The Cobb angle, the visual analog scale (VAS) and the Frankel classification were used to evaluate the effects of the surgery. The VAS, anterior and middle vertebral heights and the Cobb angle were improved significantly one day postoperatively and at the final follow-up compared with the preoperative examinations (P<0.05). No significant differences were observed between the one-day postoperative results and those at final follow-up (P>0.05). The neurological function of all patients was improved by at least one Frankel grade. All patients in this study exhibited intravertebral clefts, and postoperative pathology revealed bone necrosis. One patient (not included in this study) showed an intravertebral cleft, but the pathology report indicated a non-Hodgkin's lymphoma. The intravertebral cleft sign is not pathognomonic of Kummell's disease. Posterior decompression with short-segment fixation and fusion combined with vertebroplasty is an effective treatment for Kummell's disease with neurological deficits.
机译：这项研究的目的是调查患有神经功能缺损的库梅尔氏病的治疗方法，并确定椎间隙是否是库梅尔氏病的病理标志。最初总共被诊断出患有Kummell病的17名患者被收治，其中一名患者被排除在本研究之外。对患椎进行后路减压和椎体成形术。椎弓根螺钉固定和后外侧植骨在患椎骨上方一层和下方一层进行。提取椎骨组织用于组织病理学检查。平均随访时间为22个月（范围18到42个月）。在手术前，术后一天以及最后的随访中，在站立的侧位X光片上测量椎体的前，中椎高度。使用Cobb角，视觉模拟评分（VAS）和Frankel分类来评估手术效果。与术前检查相比，术后一天及最后一次随访时，VAS，椎体前，中椎高度和Cobb角均得到明显改善（P <0.05）。术后一日疗效与最终随访比较差异无统计学意义（P> 0.05）。所有患者的神经功能至少改善了1级Frankel。该研究中所有患者均表现出椎骨裂痕，术后病理显示骨坏死。一名患者（未包括在本研究中）显示出椎骨内裂，但病理报告显示为非霍奇金淋巴瘤。椎骨内裂征不是库默尔病的病理特征。后路减压结合短节段固定融合融合椎体成形术是治疗神经功能缺损的库梅尔氏病的有效方法。

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