• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Expert opinion on pharmacotherapy >Treatment strategies for cancer patients with breakthrough pain.
【24h】

Treatment strategies for cancer patients with breakthrough pain.

机译：突破性疼痛的癌症患者的治疗策略。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

BACKGROUND: Breakthrough pain (BTP) is a transitory flare of pain superimposed on an otherwise stable pain pattern in patients treated with opioids. It is normally severe in intensity, has a rapid onset, has a variable duration (on average 30 min) and is considered a negative prognostic factor. OBJECTIVE: To verify the data in the literature about therapy strategies for BTP in cancer patients. METHODS: To find clinical trials investigating drug therapy for BTP. CONCLUSION: The treatment of BTP in cancer patients receiving opioids is principally based on the use of opioids, preferentially with a short onset. Fentanyl delivered by recently developed systems seems to be the best option to cover the temporal pattern of BTP, although the treatment should be highly personalized to provide the best in individuals, balancing patients' preferences and clinical needs. The doses to be administered is still a matter of controversy in the literature; additional studies with specific designs should be conducted to settle the question.
机译：背景：突破性疼痛（BTP）是一种短暂的疼痛发作，叠加在使用阿片类药物治疗的患者的原本稳定的疼痛模式上。它通常强度高，起病快，持续时间可变（平均30分钟），被认为是阴性的预后因素。目的：验证有关癌症患者BTP治疗策略的文献资料。方法：寻找对BTP进行药物治疗的临床试验。结论：接受阿片类药物的癌症患者的BTP治疗主要是基于使用阿片类药物，优选起效时间短。尽管应该高度个性化的治疗以提供最佳的个人治疗效果，同时兼顾患者的喜好和临床需求，但由最近开发的系统提供的芬太尼似乎是覆盖BTP时间模式的最佳选择。给药剂量在文献中仍存在争议。应该进行其他具有特定设计的研究以解决该问题。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号