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Relationship between perifoveal capillaries and pathomorphology in macular oedema associated with branch retinal vein occlusion

机译:黄斑水肿伴视网膜分支静脉阻塞的黄斑中心凹毛细血管与病理形态的关系

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Purpose: To study the relationship between macular ischaemia on fluorescein angiography (FA) and pathomorphology at the foveal centre delineated by spectral-domain optical coherence tomography (OCT) in macular oedema (MO) associated with branch retinal vein occlusion (BRVO). Methods: One hundred and five consecutive eyes of 105 patients with MO (centre point thickness (CPT) ≥300 μm) associated with BRVO in which FA using Heidelberg Retinal Angiography 2 and Spectralis OCT were performed on the same day were retrospectively reviewed. We evaluated the foveal pathomorphology using OCT images and the association with macular ischaemia. Results: Within 1 year from symptom onset, 94 eyes were classified with perfused macula (34 eyes) or non-perfused macula (60 eyes). Eyes with perfused macula had better visual acuity and less CPT than those with non-perfused macula (P=0.024 and P<0.001, respectively). Fourteen eyes with perfused macula had serous retinal detachment (SRD) alone at the presumed foveal centre (SRD type); seven, a sponge-like swelling at that area (retinal swelling type); 11, foveal cystoid spaces alone (cystoid MO (CMO) type), and 2, with both SRD and foveal cystoid spaces (SRD+CMO type). However, 58 eyes with non-perfused macula had foveal cystoid spaces (42 of CMO type and 16 of SRD+CMO type), with a significant association between them (P<0.001). Among 11 eyes with symptoms exceeding 1 year, 6 eyes had perfused macula, and none had the SRD type. Conclusion: Most eyes without foveal cystoid spaces have perfused macula in MO associated with BRVO.
机译:目的:研究荧光光谱血管造影(OCT)在视网膜黄斑水肿(MO)与分支视网膜静脉闭塞(BRVO)相关的黄斑缺血性荧光血管造影(FA)与黄斑中心的病理形态之间的关系。方法:回顾性分析105例105例合并BRVO的MO(中心厚度(CPT)≥300μm)的MO患者的临床资料,其中在同一天使用Heidelberg Retinal Angioography 2和Spectralis OCT行FA。我们使用OCT图像评估了黄斑中央凹的形态,并与黄斑缺血相关。结果:从症状发作开始的一年内,有94眼被分类为灌注黄斑(34眼)或未灌注黄斑(60眼)。与未灌注黄斑的眼睛相比,灌注黄斑的眼睛具有更好的视敏度和更低的CPT(分别为P = 0.024和P <0.001)。十四眼黄斑灌注在假定的中央凹中心处(SRD型)仅存在浆液性视网膜脱离(SRD)。七,在该区域海绵状肿胀(视网膜肿胀型); 11,单独的中央凹囊状间隙(囊状MO(CMO)类型)和2,同时具有SRD和中央凹囊状间隙(SRD + CMO类型)。然而,有58眼未灌注黄斑具有中央凹囊状间隙(CMO型为42个,SRD + CMO型为16个),它们之间具有显着相关性(P <0.001)。在症状超过1年的11眼中,有6眼灌注了黄斑,而没有SRD型。结论:大多数无中央凹囊状间隙的眼睛在MO​​中伴BRVO灌注黄斑。

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