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The hunger hormone ghrelin in cachexia.

机译:饥饿激素生长激素释放肽在恶病质中。

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Cachexia is characterized by reduced food intake, muscle and adipose tissue loss associated with increased energy expenditure. Cachexia is highly prevalent and represents one of the main causes of increased morbidity, mortality and reduced quality of life in chronic diseases. Ghrelin plays an important role in stimulating and controlling hunger and maintaining energy homeostasis acting on central nervous system and on peripheral tissues. Most of the studies have been conducted in experimental settings and in cancer and uremic patients, showing interesting results in the treatment of cachexia. Further investigations are mandatory to obtain more definitive and conclusive results.
机译:恶病质的特征在于食物摄入减少,肌肉和脂肪组织损失与能量消耗增加有关。恶病质非常普遍,并且代表慢性病发病率,死亡率增加和生活质量下降的主要原因之一。 Ghrelin在刺激和控制饥饿以及维持作用于中枢神经系统和周围组织的能量稳态方面起着重要作用。大多数研究是在实验环境以及癌症和尿毒症患者中进行的,在恶病质的治疗中显示出有趣的结果。必须进行进一步的调查才能获得更确定的结论性结果。

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