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Chapter 4: functions of RAB and SNARE proteins in plant life.

机译:第4章:RAB和SNARE蛋白在植物生命中的功能。

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In all eukaryotic cells, vesicular trafficking is crucial for maintaining cellular and organelle functions. RABs and SNAREs play key roles in vesicle/organelle identity and exchange. Budding yeast genetics and mammalian cell biochemistry were the most effective approaches for investigating molecular mechanisms underlying vesicular trafficking and remain important in exploring new horizons. The field of vesicular trafficking attracted plant biologists in the early 1990s. Today, this field continues to stimulate a wide range of research. This review starts with some history of RAB and SNARE research in yeast and mammals and introduces a widely accepted general model. Then we summarize recent reports regarding plant RABs and SNAREs, focusing on functional diversity. Finally, we discuss how plants assign new roles to conserved vesicular trafficking proteins to perform divergent, higher order plant functions. Plants have apparently evolved a unique set of plant-specific RAB and SNARE molecules that play significant roles in plant life.
机译:在所有的真核细胞中,水泡运输对于维持细胞和细胞器功能至关重要。 RAB和SNARE在小泡/细胞器的识别和交换中起关键作用。萌芽期酵母遗传学和哺乳动物细胞生物化学是研究潜在的囊泡运输分子机制的最有效方法,并且在探索新视野方面仍然很重要。在1990年代初期,水泡运输领域吸引了植物生物学家。时至今日,该领域继续激发着广泛的研究。这篇综述从酵母和哺乳动物的RAB和SNARE研究的一些历史开始,并介绍了一种被广泛接受的通用模型。然后,我们总结了有关植物RAB和SNARE的最新报告,重点是功能多样性。最后,我们讨论植物如何赋予保守的水泡运输蛋白新的角色以执行发散的,更高阶的植物功能。植物显然已经进化出一组独特的植物特异性RAB和SNARE分子,它们在植物生命中发挥着重要作用。

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