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Antibody response after immunization with a Salmonella Typhimurium live vaccine in dependence on the way of application

机译:鼠伤寒沙门氏菌活疫苗免疫后的抗体反应取决于应用方式

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摘要

In Germany now, the recognition of Salmonella infections in pig herds is based on three different commercial tests detecting antibodies against Salmonella-derived lipopolysaccharide (LPS). However, a serious disadvantage of these tests, used so far, is the restricted detection of antibodies belonging predominantly to the immunoglobulin class g (IgG). Therefore, a new test was developed to detect three Ig classes (IgM, IgG and IgA). Different constellations between the three Ig classes allow the evaluation of the current infection status of each pig. Under field conditions, this was proved in three different vaccination trials using a commercial Salmonella Typhimurium live vaccine.
机译:现在在德国,对猪群中沙门氏菌感染的识别基于检测沙门氏菌来源的脂多糖(LPS)抗体的三种不同的商业测试。然而,迄今为止使用的这些测试的严重缺点是对主要属于免疫球蛋白g类(IgG)的抗体的检测受限。因此,开发了一种新的检测方法来检测三种Ig类(IgM,IgG和IgA)。三种Ig类之间的星座不同,可以评估每只猪的当前感染状况。在野外条件下,使用商业性鼠伤寒沙门氏菌活疫苗在三个不同的疫苗接种试验中证明了这一点。

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