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首页> 外文期刊>Canadian journal of ophthalmology >Corneal curvature and central corneal thickness in eyes with pseudoexfoliation syndrome.
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Corneal curvature and central corneal thickness in eyes with pseudoexfoliation syndrome.

机译：假性剥脱综合征患者的角膜曲率和中央角膜厚度。

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BACKGROUND: Previous studies have reported different central corneal thickness (CCT) values in eyes with pseudoexfoliation syndrome (PXS). There has been no report about corneal curvature (CC) in PXS eyes. The aim of this study was to investigate the CCT together with the CC in PXS eyes with and without glaucoma. METHODS: The CC (simulated keratometry 1 [SimK1], SimK2, and mean K) and CCT were prospectively studied by rotating a Scheimpflug camera in 72 PXS eyes and comparing them with 65 normal eyes. RESULTS: In all PXS eyes, the mean K was significantly steeper than in control eyes (44.1 [SD 1.5] diopters (D) vs. 43.2 [SD 2.0] D, p = 0.04). When PXS eyes were subcategorized, the mean K was significantly steeper in both normotensive PXS eyes (44.6 [SD 1.6] D) and pseudoexfoliation glaucoma (PEXG) eyes (44.0 [SD 1.2] D) than normal eyes (43.2 [SD 2.0] D) (p = 0.001 and 0.02, respectively). In all PXS eyes, the mean CCT (546.4 [SD 39.6] microm) was not significantly different than the control eyes (542.9 [SD 32.2] microm) (p = 0.56). When PXS eyes were subcategorized, however, the CCT was significantly thinner in normotensive PXS eyes and significantly thicker in PEXG eyes. INTERPRETATION: It appears that PEXG eyes have a significantly steeper CC and higher CCT than normal eyes. This could be of clinical significance because overestimation of true intraocular pressure may then occur in these eyes.
机译：背景：先前的研究报道了假性剥脱综合征（PXS）眼睛的中央角膜厚度（CCT）值不同。尚未有关于PXS眼睛角膜曲率（CC）的报道。这项研究的目的是研究伴有和不伴有青光眼的PXS眼睛的CCT和CC。方法：前瞻性地研究了旋转Scheimpflug相机在72头PXS眼睛中的CC（模拟角膜测定法1 [SimK1]，SimK2和均值K）和CCT，并将其与65只正常眼睛进行了比较。结果：在所有PXS眼睛中，平均K值均显着高于对照眼睛（44.1 [SD 1.5]屈光度（D）与43.2 [SD 2.0] D，p = 0.04）。将PXS眼分类后，血压正常的PXS眼（44.6 [SD 1.6] D）和假性剥脱性青光眼（PEXG）眼（44.0 [SD 1.2] D）的平均K值均比正常眼（43.2 [SD 2.0] D ）（分别为0.001和0.02）。在所有PXS眼中，平均CCT（546.4 [SD 39.6]微米）与对照眼（542.9 [SD 32.2]微米）没有显着差异（p = 0.56）。但是，如果将PXS眼睛分类，则在正常血压的PXS眼睛中，CCT显着变细，而在PEXG眼睛中，CCT显着变厚。解释：看来，PEXG眼睛比正常眼睛的CC明显陡峭，CCT更高。这可能具有临床意义，因为在这些眼睛中可能会高估真实眼内压。

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