...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Fish Physiology and Biochemistry >Gonadotrophin-releasing hormone agonist raises plasma concentrations of progestogens and enhances milt fluidity in male Atlantic halibut (Hippoglossus hippoglossus).
【24h】

Gonadotrophin-releasing hormone agonist raises plasma concentrations of progestogens and enhances milt fluidity in male Atlantic halibut (Hippoglossus hippoglossus).

机译：促性腺激素释放激素激动剂可提高雄性大西洋大比目鱼（Hippoglossus hippoglossus）中孕激素的血浆浓度并提高其流动性。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

In two separate spawning seasons, spermiating male Atlantic halibut were implanted with pellets containing gonadotropin-releasing hormone agonist (GnRHa). Males were bled repeatedly, and milt samples were collected. Blood samples were assayed for free and conjugated steroids: testosterone, 11-ketotestosterone, 17,20alpha-dihydroxy-4-pregnen-3-one (17,20alpha-P), 17,20beta-dihydroxy-4-pregnen-3-one (17,20beta-P), 17,20beta,21-trihydroxy-4-pregnen-3-one and steroids with a 17,20beta configuration. Towards the end of the first season, pellets were implanted into three wild-caught and three hatchery-reared males. No control fish were available. The major progestogen in plasma was identified as sulphated 5beta-pregnane-3beta,17,20beta-triol (3beta,17,20beta-P-5beta-S). Concentrations of this steroid were stimulated by the GnRHa. Sulphated 17,20beta-P was also identified in the plasma, but at 10-fold lower concentrations than 3beta,17,20beta-P-5beta-S. In the middle of the second season, pellets were implanted into five hatchery-reared males; five unimplanted males were used as controls. Levels of androgens fell following GnRHa treatment, levels of progestogens rose briefly, and there was a significant increase in the fluidity of the milt. Of all themeasured steroids, free and sulphated 17,20alpha-P showed the best correlation with milt fluidity.
机译：在两个单独的产卵季节中，向生精的雄性大比目鱼植入含有促性腺激素释放激素激动剂（GnRHa）的药丸。雄性反复抽血，并收集鱼糜样品。分析血液样本中游离和结合的类固醇：睾丸激素，11-酮睾丸酮，17,20α-二羟基-4-孕烯-3-酮（17,20alpha-P），17,20β-二羟基-4-孕烯-3-酮（17,20beta-P），17,20beta，21-三羟基-4-孕烯-3-酮和类固醇具有17,20beta构型。在第一个季节即将结束时，将颗粒植入三只野生捕捞和三只孵化场饲养的雄性中。没有对照鱼。血浆中的主要孕激素被鉴定为硫酸化的5beta-孕烯-3beta，17,20beta-三醇（3beta，17,20beta-P-5beta-S）。 GnRHa刺激了该类固醇的浓度。在血浆中也鉴定出硫酸化的17,20beta-P，但浓度比3beta，17,20beta-P-5beta-S低10倍。在第二季的中段，将粒状食物植入五只孵化场饲养的雄性中。五只未植入的雄性用作对照。 GnRHa治疗后雄激素水平下降，孕激素水平短暂上升，并且鱼mi的流动性显着增加。在所有测得的类固醇中，游离的和硫酸化的17,20alpha-P显示出与麦芽流动性的最佳相关性。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号