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首页> 外文期刊>Marine genomics >Permanent draft genome sequence of Bacillus flexus strain T6186-2, a multidrug-resistant bacterium isolated from a deep-subsurface oil reservoir
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Permanent draft genome sequence of Bacillus flexus strain T6186-2, a multidrug-resistant bacterium isolated from a deep-subsurface oil reservoir

机译：弯曲芽孢杆菌T6186-2菌株的永久基因组序列，该菌株是从深地下油藏中分离出来的一种多药耐药细菌

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摘要

Previous studies suggest that antibiotic resistance genes have an ancient origin, which is not always linked to the use of antibiotics but can be enhanced by human activities. Bacillus flexus strain T6186-2 was isolated from the formation water sample of a deep-subsurface oil reservoir. Interestingly, antimicrobial susceptibility testing showed that this strain is susceptible to kanamycin, however, resistant to ampicillin, erythromycin, gentamicin, vancomycin, fosfomycin, fosmidomycin, tetracycline and teicoplanin. To explore our knowledge about the origins of antibiotic resistance genes (ARGs) in the relatively pristine environment, we sequenced the genome of B. flexus strain T6186-2 as a permanent draft. It represents the evidence for the existence of a reservoir of ARGs in nature among microbial populations from deep-subsurface oil reservoirs. (c) 2014 Elsevier B.V. All rights reserved.
机译：先前的研究表明，抗生素抗性基因具有悠久的渊源，它并不总是与抗生素的使用有关，但可以通过人类活动来增强。从深地下油藏的地层水样品中分离出弯曲芽孢杆菌菌株T6186-2。有趣的是，抗菌药敏试验表明该菌株对卡那霉素敏感，但是对氨苄青霉素，红霉素，庆大霉素，万古霉素，磷霉素，磷霉素，四环素和替考拉宁有抗性。为了探索我们对相对原始环境中的抗生素抗性基因（ARG）起源的了解，我们对弯曲双歧杆菌菌株T6186-2的基因组进行了测序，作为一个永久草案。它代表了深地下石油储层中微生物种群中自然存在ARGs储层的证据。 （c）2014 Elsevier B.V.保留所有权利。

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