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首页> 外文期刊>Cancer epidemiology >The incidence and survival of acute de novo leukemias in Estonia and in a well-defined region of western Sweden during 1997-2001: A survey of patients aged ≥65 years
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The incidence and survival of acute de novo leukemias in Estonia and in a well-defined region of western Sweden during 1997-2001: A survey of patients aged ≥65 years

机译：1997-2001年在爱沙尼亚和瑞典西部一个明确地区的急性新发白血病的发生率和存活率：≥65岁患者的调查

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Background: In a recently published retrospective population-based study over three 5-year periods (1982-1996) we investigated the outcome for de novo acute leukemia (AL) patients aged ≥65 years at diagnosis in Estonia (a country that had been occupied by the Soviet Union over 5 decades) and in the so-called Western Swedish Health Care Region. The age-standardized yearly incidence rates regarding the total number of de novo AL was 5.3/100 000 inhabitant for Estonia and 8.0 for Sweden, this difference being statistically significant merely as regards acute myeloid leukemia (AML). The relative survival for the total cohort of de novo AL as well as for de novo AML was significantly longer (p < 0.001) for Swedish as compared to Estonian patients. Methods: In view of the miserable outcome for the Estonian patients we decided to prospectively compare the results for incidence and outcome of de novo AL between the two countries. Results: The present report covers the first 5-year period comprising 1997-2001 and deals only with patients aged ≥65 years at diagnosis. The age-adjusted annual incidence rates for de novo AML were lower in Estonia (6.4/100 000) than in Sweden (9.2/100 000) but not significantly so. The present results also show that the outcome for the Estonian AML patients had improved considerably over the study period; thus, at no time point, i.e., at 1, 3 and 5 years did relative survival between the two countries differ significantly. Conclusion: Yet, as compared to the Swedish cohort relative survival for the Estonian patients did still not reach an acceptable level.
机译：背景：在最近发表的一项基于人群的回顾性研究中，该研究历时3年（1982-1996年），历时5年，在爱沙尼亚（一个被占领的国家）中，我们调查了≥65岁的从头急性白血病（AL）患者苏联在过去的5年中）和所谓的西瑞典医疗保健地区。爱沙尼亚的从头算起AL总数的年龄标准化年发病率是5.3 / 10万，瑞典是8.0，这仅在急性髓细胞性白血病（AML）方面具有统计学意义。与爱沙尼亚患者相比，瑞典人从头开始的总生存期和AML从头开始的相对生存期明显更长（p <0.001）。方法：鉴于爱沙尼亚患者的悲惨结局，我们决定前瞻性地比较两国之间的新生代AL发生率和结局结果。结果：本报告涵盖从1997年至2001年的前5年，仅针对诊断时≥65岁的患者。在爱沙尼亚，按年龄调整的新发AML的年发病率（6.4 / 100 000）低于瑞典（9.2 / 100 000），但并非如此。目前的结果还表明，在研究期间，爱沙尼亚AML患者的结局已有很大改善。因此，在任何时候，即1年，3年和5年，两国之间的相对生存率都没有显着差异。结论：然而，与瑞典队列相比，爱沙尼亚患者的相对存活率仍未达到可接受的水平。

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