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Enhanced physiology for submaximal exercise in children after the fontan procedure.

机译:the门手术后儿童次最大运动的增强生理功能。

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After the Fontan procedure, children exhibit reduced peak exercise capacity, yet their submaximal exercise response remains unclear. This study sought to determine the relationship between submaximal and peak exercise capacity and physical activity in Fontan patients.This cross-sectional study recruited 50 Fontan patients (59% males) with a median age of 9 yr (range = 6-12 yr). The median age at Fontan procedure was 2.9 yr (range = 1.6-9.1 yr). Study assessments included medical history, exercise testing, and accelerometry.Significantly lower submaximal oxygen consumption (V˙O2) and HR in response to a standardized workload than published values for healthy children (mean ± SD) of -1.72 ± 5.24 (P < 0.001) and -1.45 ± 1.98 (P < 0.001), respectively, suggest enhanced submaximal work efficiency in this group of patients after Fontan. Higher submaximal V˙O2 z-score was associated with higher submaximal HR z-score (P = 0.02) and lower body mass index z-score (P = 0.01). Higher V˙O2peak was associated with higher submaximal V˙O2 z-score (P < 0.01), male sex (P = 0.03), higher RER (P = 0.02), lower submaximal HR z-score (P < 0.01), and higher chronotropic responsiveness (P < 0.0001). Exercise test duration z-score was associated with lower submaximal HR z-score (P = 0.02) and higher chronotropic responsiveness (P = 0.02).Fontan patients exhibited a lower submaximal V˙O2 and HR responsiveness at a given workload than healthy controls did during standardized exercise testing. Thus, they may be better adapted to perform submaximal exercise. Although peak exercise capacity is limited, Fontan patients are able to perform submaximal physical activities at the same level as their healthy peers.
机译:丰坦手术后,儿童表现出的峰值运动能力下降,但是他们最大的运动反应仍不清楚。这项研究试图确定Fontan患者的亚最大和最大运动能力与身体活动之间的关系。这项横断面研究招募了50位Fontan患者(男性占59%),中位年龄为9岁(范围= 6-12岁)。丰坦手术的中位年龄为2.9岁(范围= 1.6-9.1岁)。研究评估包括病史,运动测试和加速度计。对标准化工作量的反应中,最大最大耗氧量(V˙O2)和HR显着低于健康儿童的公布值(平均值±SD)-1.72±5.24(P <0.001 )和-1.45±1.98(P <0.001),分别表明Fontan术后这组患者的次最大工作效率得到了提高。较高的V subO2 z评分较高与较高的HR z评分较低(P = 0.02)和较低的体重指数z评分(P = 0.01)相关。较高的V˙O2peak与较高的V˙O2z分数较高(P <0.01),男性(P = 0.03),较高的RER(P = 0.02),较低的最大HR z分数(P <0.01)和更高的变时响应性(P <0.0001)。运动测试持续时间z评分与较低的最大HR z评分(P = 0.02)和较高的变时反应性(P = 0.02)相关。与健康对照组相比,在一定工作量下,Fontan患者的V˙O2和HR反应性低于最大在标准化运动测试中。因此,它们可能更好地适于进行次最大运动。尽管峰值运动能力有限,但Fontan患者能够以与健康同龄人相同的水平进行次最大的体育锻炼。

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