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Cancer among Asian Indians/Pakistanis living in the United States: low incidence and generally above average survival.

机译:居住在美国的亚洲印第安人/巴基斯坦人中的癌症:低发病率,普遍高于平均生存率。

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BACKGROUND: South Asian immigrants living in the United Kingdom and Canada have been found to have lower rates of cancers of all types compared with the native born population and most other immigrant groups. Cancer among Asian Indian/Pakistani people in the United States has been studied very little. METHODS: Incidence rates for all cancers combined and site-specific rates for major cancers were estimated for Asian Indians/Pakistani population using incidence data from the U.S. National Cancer Institutes SEER database and population data from the U.S. Census Bureau. Site-specific survival was compared for major cancer sites between Asian Indians/Pakistanis and Caucasians using Cox proportional hazards models. RESULTS: Cancer rates for Asian Indian/Pakistani males and females were considerably lower than for White Americans with standardized incidence ratios (SIRs) of 0.46 (95% CI = 0.44, 0.48), and 0.55 (95% CI = 0.53, 0.58) respectively. Site-specific rates were lower for both genders for most sites with particularly low rates observed for lung, colorectal, female breast, and prostate cancer. Among common cancers sites, survival was generally better among Asian Indians/Pakistanis than Caucasians with the notable exception of breast cancer for which Caucasians had slightly better survival. CONCLUSIONS: The finding that Asian Indians/Pakistanis in the United States have relatively low incidence rates for most major cancers is consistent with studies from other countries. Whether the low incidence of cancer and above average cancer survival for this group is related to their well-above average socioeconomic status or cultural and behavioral factors is a topic for further research.
机译:背景:与本地出生人口和大多数其他移民群体相比,生活在英国和加拿大的南亚移民发现的所有类型癌症的发病率均较低。在美国的亚洲印度裔/巴基斯坦裔人群中,癌症的研究很少。方法:使用美国国家癌症研究所SEER数据库的发病率数据和美国人口普查局的人口数据,估算了亚洲印第安人/巴基斯坦人口的所有癌症综合发病率和主要癌症的特定部位发生率。使用Cox比例风险模型比较了亚洲印第安人/巴基斯坦人和高加索人之间主要癌症部位的特定部位生存率。结果:亚洲印度裔/巴基斯坦男性和女性的癌症发生率分别比标准比率为0.46(95%CI = 0.44,0.48)和0.55(95%CI = 0.53,0.58)的美国白人低得多。 。在大多数地点,两种性别的地点特异性比率都较低,其中肺癌,大肠癌,女性乳腺癌和前列腺癌的比率特别低。在常见的癌症部位中,亚洲印第安人/巴基斯坦人的生存率通常比白种人高,但值得注意的是乳腺癌,白种人的生存率略高。结论:美国亚裔印度人/巴基斯坦人对大多数主要癌症的发生率相对较低,这一发现与其他国家的研究一致。该组癌症的低发率和高于平均水平的癌症存活率是否与他们高于平均水平的社会经济状况或文化和行为因素有关是进一步研究的话题。

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