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首页> 外文期刊>Cancer nursing >Factors relating to quality of life after esophagectomy for cancer patients in Taiwan
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Factors relating to quality of life after esophagectomy for cancer patients in Taiwan

机译：台湾癌症患者食管切除术后生活质量的相关因素

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Background: Little is known regarding the short-term quality of life (QoL) and predictive factors for QoL after esophagectomy for cancer in Eastern countries. Objective: The aims of this study were to assess QoL and symptoms within 1 and 6 months after surgery for esophageal cancer (EC) and to identify factors predictive of QoL within 6 months after esophagectomy in Taiwan. Methods: A longitudinal, prospective design was used, where convenience samples of 99 patients who had undergone esophagectomy for cancer were recruited from 2 medical centers in northern Taiwan. All participants responded to a questionnaire with a QLQ-C30 (Quality of Life Questionnaire-Cancer) core and a QLQ-OES18 (esophageal module of the European Organization for Research and Treatment [EORTC] QLQ-C30) module in structured interviews at baseline and 1 and 6 months after surgery. Results: The results showed significant decline in social function and global QoL; fatigue, insomnia, eating problems, reflux, and dry mouth were major problems within 6 months. Body mass index, body weight loss before surgery, activity performance status, and anastomosis site showed no significant association with the function and symptom aspect of QoL. Surgical complications, advanced cancer, neoadjuvant therapy before surgery, and tumor location other than at the EC junction had significant deleterious effects on several aspects of QoL. Conclusions: This study describes the demographics of EC and short-term changes in QoL and also the predictive impact factor for QoL after surgery for EC. Implications for practice: Knowledge of risk factors for poor postoperative QoL would be useful for health providers in detecting and prioritizing problems and treatment options in a busy clinical site.
机译：背景：在东方国家，对于食管癌切除术后癌症的短期生活质量（QoL）和QoL的预测因素知之甚少。目的：本研究的目的是评估台湾食管癌手术后1和6个月内的QoL和症状，并确定食管切除术后6个月内的QoL预测因素。方法：采用纵向，前瞻性设计，从台湾北部两个医疗中心招募了99例接受食管癌切除术的癌症患者。所有参与者均在基线和结构化访谈中以QLQ-C30（生活质量问卷-癌症）核心和QLQ-OES18（欧洲研究与治疗组织[EORTC] QLQ-C30食管模块）模块回答了问卷。术后1个月和6个月。结果：结果显示社交功能和全球生活质量显着下降;疲劳，失眠，饮食问题，反流和口干是6个月内的主要问题。体重指数，术前体重减轻，活动表现状态和吻合部位与QoL的功能和症状方面无显着相关性。手术并发症，晚期癌症，术前新辅助疗法以及除EC交界处的肿瘤位置对QoL的多个方面均具有显着的有害影响。结论：本研究描述了EC的人口统计学和QoL的短期变化，以及EC术后的QoL预测影响因素。实践的意义：术后QoL差的危险因素知识对于健康服务提供者在繁忙的临床站点中发现问题和治疗方案并对其进行优先级排序时将非常有用。

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