IN VIVO RADIOPROTECTIVE EFFECT OF CHLOROPHYLLIN ON SISTER CHROMATID EXCHANGE INDUCTION IN MURINE SPERMATOGONIAL CELLS

Moralesramirez P; Mendiolacruz MT

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IN VIVO RADIOPROTECTIVE EFFECT OF CHLOROPHYLLIN ON SISTER CHROMATID EXCHANGE INDUCTION IN MURINE SPERMATOGONIAL CELLS

机译：叶绿素对小鼠精原细胞中染色体突变交换诱导的体内放射防护作用

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摘要

The radioprotective capacity of chlorophyllin was determined by measuring the reduction of gamma-ray-induced sister chromatid exchange (SCE) in murine spermatogonia in vivo. The results obtained in experiments using 100 and 200 mu g of chlorophyllin per gram of body weight (bw) and irradiated either before or after BrdU incorporation, indicate that a chlorophyllin dose of 200 mu g/g bw protects 100% against the induction of SCE by 0.75 Gy of gamm-rays and 100 mu g/g bw protects less than 50%. Chlorophyllin per se did not have any effect on the SCE frequency.

机译：叶绿素的辐射防护能力是通过测量体内小鼠精子中γ射线诱导的姐妹染色单体交换（SCE）的减少来确定的。在每克体重（bw）中使用100和200μg叶绿素的实验结果，并在掺入BrdU之前或之后进行辐照，结果表明200μg / g bw的叶绿素剂量可100％防止SCE的诱导0.75 gy的gam射线和100μg / g的bw防护不到50％。叶绿素本身对SCE频率没有任何影响。

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《Mutation research. Genetic toxicology testing》 |1995年第2期|共6页
作者
Moralesramirez P; Mendiolacruz MT;
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正文语种 eng
中图分类遗传学;
关键词
Bone marrow cells; Hamster ovary cells; Gamma radiation; Antimutagenic; activity; Human lymphocytes; Complex mixtures; Strand breaks; Invivo; Rays; Inhibition;

机译：骨髓细胞;仓鼠卵巢细胞;伽马射线;抗诱变;活性;人淋巴细胞;复杂混合物;链断裂;体内;射线;抑制;

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1. IN VIVO RADIOPROTECTIVE EFFECT OF CHLOROPHYLLIN ON SISTER CHROMATID EXCHANGE INDUCTION IN MURINE SPERMATOGONIAL CELLS [J] . Moralesramirez P, Mendiolacruz MT Mutation research. Genetic toxicology testing . 1995,第1a2期

机译：叶绿素对小鼠精原细胞中染色体突变交换诱导的体内放射防护作用
2. Differences in sensitivity of murine spermatogonia and somatic cells in vivo to sister-chromatid exchange induction by nitrosoureas [J] . Morales-Ramirez P., Rodriguez-Reyes R., Cruz-Vallejo V. Mutation Research: International Journal on Mutagenesis, Chromosome Breakage and Related Subjects . 2001,第1a2期

机译：小鼠精原细胞和体细胞对亚硝基脲诱导姐妹染色单体交换的敏感性差异
3. In vivo effect of gamma ray pretreatment on sister-chromatid exchange induction by mitomycin C in murine bone marrow cells. [J] . Morales Ramirez P, Cruz Vallejo V Mutation Research: International Journal on Mutagenesis, Chromosome Breakage and Related Subjects . 1996,第4期

机译：γ射线预处理对小鼠骨髓细胞中丝裂霉素C诱导姐妹染色单体交换的体内作用。
4. Evaluation of radioprotection properties of propolis by chromosomal alterations, cell proliferation kinetics, mitotic index and sister chromatid exchange. [C] . Alegria Montoro, Joan Francesc Barquinero, Miguel Almonacid, Congress of the International Radiation Protection Association;IRPA 12 . 2010

机译：通过染色体改变，细胞增殖动力学，有丝分裂指数和姐妹染色单体交换评估蜂胶的辐射防护特性。
5. FREQUENCY OF SISTER CHROMATID EXCHANGES AND CELL CYCLE KINETICS IN CULTURED HUMAN LYMPHOCYTES TREATED WITH SELENIUM ALONE OR SELENIUM AND METHYLNITROSOUREA. [D] . KHALIL, AHMAD MOHAMMAD. 1987

机译：硒单独或硒和亚甲基亚硝基脲处理的人淋巴细胞中的染色体染色交换和细胞周期动力学的频率。
6. Cytogenetic effects of inhaled benzene in murine bone marrow: induction of sister chromatid exchanges chromosomal aberrations and cellular proliferation inhibition in DBA/2 mice. [O] . R R Tice, D L Costa, R T Drew 1980

机译：吸入苯在小鼠骨髓中的细胞遗传学作用：诱导姐妹染色单体交换染色体畸变和DBA / 2小鼠细胞增殖抑制。
7. Induction of sister chromatid exchanges by cypermethrin and carbosulfan in bone marrow cells of mice in vivo [O] . S. Giri 2003

机译：在体内小鼠骨髓细胞骨髓细胞中染色乳蛋白和碳酸的诱导症
8. Kinetics of In vivo Sister Chromatid Exchange Induction in Mouse Bone Marrow Cells in Ethylnitrosourea and Methylnitrosourea [R] . Charles, J. L. , Jacobson-Kram, D. , Condie, L. , 1986

机译：乙基亚硝基脲和甲基亚硝基脲对小鼠骨髓细胞体内姐妹染色单体交换诱导的动力学

IN VIVO RADIOPROTECTIVE EFFECT OF CHLOROPHYLLIN ON SISTER CHROMATID EXCHANGE INDUCTION IN MURINE SPERMATOGONIAL CELLS

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