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The developmental genetics of homology

机译:同源性的发育遗传学

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Homology is an essential idea of biology, referring to the historical continuity of characters, but it is also conceptually highly elusive. The main difficulty is the apparently loose relationship between morphological characters and their genetic basis. Here I propose that it is the historical continuity of gene regulatory networks rather than the expression of individual homologous genes that underlies the homology of morphological characters. These networks, here referred to as 'character identity networks', enable the execution of a character-specific developmental programme.
机译:同源性是生物学的基本概念,是指字符的历史连续性,但从概念上讲也是高度难以捉摸的。主要的困难是形态特征与其遗传基础之间明显的松散关系。在这里,我提出,基因调控网络的历史连续性而不是单个同源基因的表达是形态特征同源性的基础。这些网络,这里称为“角色识别网络”,可以执行特定于角色的开发程序。

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