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首页> 外文期刊>Nature reviews. Urology >The role of lymphadenectomy for upper tract urothelial carcinoma.
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The role of lymphadenectomy for upper tract urothelial carcinoma.

机译：淋巴结清扫术在上尿路尿路上皮癌中的作用。

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Regional lymphadenectomy, with both its diagnostic and therapeutic roles, serves as an integral component of the management of many malignancies. Extended pelvic lymph node dissection (LND) is the standard of care for urothelial carcinoma of the bladder, with the extent of lymphadenectomy correlating positively with cancer-related outcomes. Given their histologic similarities with bladder cancer, it is reasonable to hypothesize that a similar relationship exists for upper tract urothelial carcinomas (UTUCs). However, the data published to date have failed to consistently demonstrate a therapeutic benefit of regional LND for UTUC. As a consequence, utilization of regional lymphadenectomy remains at the discretion of the surgeon, the extent of LND lacks standardization, and its clinical utility continues to be debated. In order to better clarify the existing data, we present a review of the role of regional lymphadenectomy in patients with UTUC.
机译：具有诊断和治疗作用的局部淋巴结清扫术是许多恶性肿瘤治疗不可或缺的组成部分。盆腔扩大淋巴结清扫术（LND）是膀胱尿路上皮癌的治疗标准，淋巴结清扫术的程度与癌症相关的结果呈正相关。鉴于它们与膀胱癌的组织学相似性，可以合理地假设上尿路尿路上皮癌（UTUC）存在相似的关系。但是，迄今为止公布的数据未能始终证明区域性LND对UTUC有治疗益处。结果，局部淋巴结清扫术的使用仍由外科医生决定，LND的程度缺乏标准化，其临床实用性仍在争论中。为了更好地阐明现有数据，我们对区域淋巴结清扫术在UTUC患者中的作用进行了综述。

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