Childhood chronic inflammatory demyelinating polyneuropathy with central nervous system demyelination resembling multiple sclerosis.

Rodriguez Casero MV; Shield LK; Coleman LT; Kornberg AJ

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Childhood chronic inflammatory demyelinating polyneuropathy with central nervous system demyelination resembling multiple sclerosis.

机译：儿童慢性发炎性脱髓鞘性多发性神经病，中枢神经系统脱髓鞘，多发性硬化。

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Central nervous system demyelination has been described in adults but not in children with chronic inflammatory demyelinating polyneuropathy. We describe a patient with clinical and electrophysiological features consistent with chronic inflammatory demyelinating polyneuropathy who presented at age 5 with an intramedullary spinal cord tumor-like lesion and at age 8, represented with cerebral and spinal demyelinating lesions. Her clinical course and magnetic resonance imaging features were atypical for multiphasic disseminated encephalomyelitis and indistinguishable from multiple sclerosis. To our knowledge, this association has not been previously described in the English literature in childhood.

机译：成人中枢神经系统脱髓鞘已有报道，但慢性炎性脱髓鞘性多发性神经病患儿则未见报道。我们描述了具有与慢性炎症性脱髓鞘性多发性神经病一致的临床和电生理学特征的患者，该患者在5岁时出现髓内脊髓肿瘤样病变，在8岁时表现为脑和脊髓性脱髓鞘病变。她的临床过程和磁共振成像特征对于多相性弥漫性脑脊髓炎是非典型的，与多发性硬化症没有区别。据我们所知，这种关联在童年时期的英语文学中还没有被描述过。

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《Neuromuscular disorders: NMD》 |2003年第2期|共4页
作者
Rodriguez Casero MV; Shield LK; Coleman LT; Kornberg AJ;
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正文语种 eng
中图分类神经病学与精神病学;
关键词
Central Nervous System Diseases; Multiple Sclerosis; Polyradiculoneuropathy; Chronic Inflammatory Demyelinating complications; 中枢神经系统疾病; 多发性硬化;

机译：Central Nervous System Diseases;Multiple Sclerosis;Polyradiculoneuropathy;Chronic Inflammatory Demyelinating complications;中枢神经系统疾病;多发性硬化;

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1. Childhood chronic inflammatory demyelinating polyneuropathy with central nervous system demyelination resembling multiple sclerosis. [J] . Rodriguez Casero MV, Shield LK, Coleman LT, Neuromuscular disorders: NMD . 2003,第2期

机译：儿童慢性发炎性脱髓鞘性多发性神经病，中枢神经系统脱髓鞘，多发性硬化。
2. Exacerbation of chronic inflammatory demyelinating polyradiculoneuropathy during interferonbeta-1b therapy in a patient with childhood-onset multiple sclerosis. [J] . Matsuse D, Ochi H, Tashiro K, Internal medicine. . 2005,第1期

机译：儿童期多发性硬化症患者干扰素β-1b治疗期间慢性炎性脱髓鞘性多发性神经根病的加重。
3. Spreading of autoimmunity from central to peripheral myelin: two cases of clinical association between multiple sclerosis and chronic inflammatory demyelinating polyneuropathy. [J] . Falcone M, Scalise A, Minisci C, Neurological sciences . 2006,第1期

机译：自身免疫从中枢至外周髓磷脂的传播：多发性硬化症与慢性炎性脱髓鞘性多发性神经病之间的临床关联的两例。
4. Chronic Inflammatory Demyelinating Polyneuropathy in an Eight Year Old Girl [C] . S. Hiz Kurul, U. Yis, O. Senocak International Conference on Diagnosis and Treatment in Pediatric Neurology . 2008

机译：八岁女孩的慢性炎症脱髓鞘多变病变
5. Therapeutic Targeting of Glial Cells in Central Nervous System Inflammatory Demyelinating Disease [D] . Thompson, Kaitlyn Koenig. 2019

机译：中枢神经系统炎症性脱髓鞘疾病中胶质细胞的治疗靶向
6. Involvement of the central nervous system in chronic inflammatory demyelinating polyneuropathy: a clinical electrophysiological and magnetic resonance imaging study. [O] . I E Ormerod, H M Waddy, A G Kermode, 1990

机译：中枢神经系统参与慢性炎性脱髓鞘性多发性神经病的临床电生理和磁共振成像研究。
7. Involvement of the central nervous system in chronic inflammatory demyelinating polyneuropathy: a clinical, electrophysiological and magnetic resonance imaging study. [O] . Ormerod, I E, Waddy, H M, Kermode, A G, 1990

机译：中枢神经系统参与慢性炎性脱髓鞘性多发性神经病的临床，电生理和磁共振成像研究。

Childhood chronic inflammatory demyelinating polyneuropathy with central nervous system demyelination resembling multiple sclerosis.

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