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首页> 外文期刊>Neuropathology: official journal of the Japanese Society of Neuropathology >Bilateral intraventricular mass in a child
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Bilateral intraventricular mass in a child

机译：儿童双侧脑室内包块

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An 8-year-old boy presented with a history of holocranial headache for 4 weeks which was mild to moderate in intensity. There was history of intermittent vomiting for the same duration. The patient was drowsy for the last 10 days. Non-contrast CT scan of head showed a space-occupying lesion in lateral ventricles with hydrocephalus. MRI showed a large lobulated well-defined heterogeneous mass lesion filling up both lateral ventricles at the posterior and temporal horns, bilaterally reaching up to the level of the foramen magnum. The mass lesion was hypointense on T2-weighted images (T2W) and isointense to grey mater on T1W images. On contrast images there was intense homogeneous enhancement seen at the lesion (Fig. 1). Right fronto-temporo-parietal craniotomy with decompression of the tumor was performed. Perioperatively, the tumor was yellowish in color, firm, not able to be aspirated and minimally vascular. Clinical diagnosis of choroid plexus tumor was considered. Pathological findings Microscopic examination revealed multiple fragments of a tumor. The tumor was composed of sheets of round to oval to spindle-shaped cells with finely granular eosinophilic cytoplasm (Fig. 2A). A significant number of cells contained foamy cytoplasm (Fig. 2B). Many interspersed xanthomatous Touton giant cells were present (Fig. 2C). Scattered lymphocytes, plasma cells and eosi-nophils were seen. No mitosis or necrosis was seen. Normal choroid plexus was identified at one place (Fig.2D).
机译：一个8岁男孩表现出全颅性头痛病史，持续4周，强度轻至中度。在相同的时间内有间歇性呕吐的历史。在过去的10天里，病人昏昏欲睡。头部的非CT扫描显示脑积水的侧脑室有占位性病变。 MRI显示，在后角和颞角的两个侧脑室都充满了一个大的，清晰的异质性肿块病灶，双侧达到了大孔的水平。在T2加权图像（T2W）上，肿块病变是低位的，而在T1W图像上，肿块是灰色的。在对比图像上，病变处可见强烈的均匀增强（图1）。进行右颞颞顶开颅手术并减压。围手术期，肿瘤呈淡黄色，结实，不能被抽吸，血管最少。考虑脉络丛神经瘤的临床诊断。病理结果镜检可见肿瘤的多个碎片。肿瘤由圆形到椭圆形到纺锤形的细胞片组成，具有细颗粒的嗜酸性细胞质（图2A）。大量细胞含有泡沫细胞质（图2B）。存在许多散布的黄瘤性Touton巨细胞（图2C）。可见散在的淋巴细胞，浆细胞和嗜酸性粒细胞。未见有丝分裂或坏死。正常的脉络丛被确定在一个地方（图2D）。

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