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首页> 外文期刊>Neuropathology: official journal of the Japanese Society of Neuropathology >Rosai-Dorfman disease isolated to the central nervous system: a report of six cases.
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Rosai-Dorfman disease isolated to the central nervous system: a report of six cases.

机译：Rosai-Dorfman病隔离到中枢神经系统：六例报告。

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摘要

We reviewed the diagnosis and treatment of six patients with CNS Rosai-Dorfman disease (RDD). Lesions were located in the cerebral convexity, middle cranial base, parasaggital, petrous orbit, and thoracic spine. Preoperatively, all the lesions were misdiagnosed as meningioma. Histopathology of all CNS lesions showed a characteristic feature called emperipolesis, where small lymphocytes or plasma cells were engulfed in histiocyte cytoplasm. Total resection of lesions was performed in all cases, and at an average follow-up of 15 months, all patients are alive and well with no evidence of recurrence. Preoperative diagnosis of CNS RDD is challenging. Surgical removal of lesions is an effective treatment. More research is needed to clarify the effectiveness of other treatment options such as radiosurgery and corticosteroid therapy.
机译：我们回顾了6例中枢神经系统Rosai-Dorfman病（RDD）的诊断和治疗。病变位于脑凸，颅中段，下颌旁，眼眶和胸椎。术前，所有病变均被误诊为脑膜瘤。所有中枢神经系统病变的组织病理学均表现出称为经验性极少的特征，即小淋巴细胞或浆细胞被吞噬到组织细胞的细胞质中。所有病例均行病变全切除术，平均随访15个月，所有患者均存活且健康，无复发迹象。术前诊断中枢神经系统RDD具有挑战性。手术切除病变是一种有效的治疗方法。需要更多的研究来阐明其他治疗选择的有效性，例如放射外科手术和糖皮质激素治疗。

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